Reactivating cue approached positive personality traits during sleep promotes positive self-referential processing

Abstract

People preferentially endorse positive personality traits as more self-descriptive than negative ones, a positivity self-referential bias. Here, we investigated how to enhance positive self-referential processing, integrating wakeful cue-approach training task (CAT) and sleep-based targeted memory reactivation (TMR). In the CAT, participants gave speeded motor responses to cued positive personality traits. In a subsequent nap, we unobtrusively re-played half of the trained positive traits during slow-wave sleep (TMR). Upon awakening, CAT+TMR facilitated participants’ speed in endorsing positive traits in immediate tests, and rendered participants endorse more positive traits as self-descriptive after one week. Notably, these enhancements were associated with the directionality of cue-related 1–4 Hz slow traveling waves (STW) that propagate across brain regions. Specifically, anterior-to-posterior backward STW was positively associated with these benefits, whereas forward STW showed negative associations. These findings demonstrate the potential benefits of integrated wakeful cue-approach training and sleep-based memory reactivation in strengthening positive self-referential processing.