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- Publisher Website: 10.1002/adfm.202402975
- Scopus: eid_2-s2.0-85195698929
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Article: Photoresponsive Drug Delivery Systems: Challenges and Progress
Title | Photoresponsive Drug Delivery Systems: Challenges and Progress |
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Authors | |
Keywords | nanoparticles photoresponse phototherapy stimuli-responsive drug delivery targeted drug delivery |
Issue Date | 12-Jun-2024 |
Publisher | Wiley |
Citation | Advanced Functional Materials, 2024 How to Cite? |
Abstract | Photoresponsive drug delivery systems (PDDSs) have emerged as a promising toolbox for drug delivery, offering precise control over the site, duration, and dosage of light-triggered medication. It allows controlled drug release, photo-triggered targeting, diagnosis, and treatment, improving the precision and efficacy of therapies for various diseases. Despite progress in designing different PDDSs, clinical translation has been limited due to various obstacles. Herein, this review article focuses on three critical challenges of PDDSs: 1) accumulation at diseased lesions, 2) precision of light irradiation, and 3) penetration of light in tissues. Also, this article summarizes and discusses current advancements and strategies to address these challenges. Overall, it emphasizes the need to clarify the current challenges from bench to bedside and develop strategies to enhance therapeutic outcomes, increase compatibility and patient compliance, and unlock the possibilities in different clinical therapies. |
Persistent Identifier | http://hdl.handle.net/10722/347168 |
ISSN | 2023 Impact Factor: 18.5 2023 SCImago Journal Rankings: 5.496 |
DC Field | Value | Language |
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dc.contributor.author | Yang, Yang | - |
dc.contributor.author | Long, Kaiqi | - |
dc.contributor.author | Chu, Yuxiu | - |
dc.contributor.author | Lu, Huiping | - |
dc.contributor.author | Wang, Weiping | - |
dc.contributor.author | Zhan, Changyou | - |
dc.date.accessioned | 2024-09-18T00:30:50Z | - |
dc.date.available | 2024-09-18T00:30:50Z | - |
dc.date.issued | 2024-06-12 | - |
dc.identifier.citation | Advanced Functional Materials, 2024 | - |
dc.identifier.issn | 1616-301X | - |
dc.identifier.uri | http://hdl.handle.net/10722/347168 | - |
dc.description.abstract | <p>Photoresponsive drug delivery systems (PDDSs) have emerged as a promising toolbox for drug delivery, offering precise control over the site, duration, and dosage of light-triggered medication. It allows controlled drug release, photo-triggered targeting, diagnosis, and treatment, improving the precision and efficacy of therapies for various diseases. Despite progress in designing different PDDSs, clinical translation has been limited due to various obstacles. Herein, this review article focuses on three critical challenges of PDDSs: 1) accumulation at diseased lesions, 2) precision of light irradiation, and 3) penetration of light in tissues. Also, this article summarizes and discusses current advancements and strategies to address these challenges. Overall, it emphasizes the need to clarify the current challenges from bench to bedside and develop strategies to enhance therapeutic outcomes, increase compatibility and patient compliance, and unlock the possibilities in different clinical therapies.<br></p> | - |
dc.language | eng | - |
dc.publisher | Wiley | - |
dc.relation.ispartof | Advanced Functional Materials | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | nanoparticles | - |
dc.subject | photoresponse | - |
dc.subject | phototherapy | - |
dc.subject | stimuli-responsive drug delivery | - |
dc.subject | targeted drug delivery | - |
dc.title | Photoresponsive Drug Delivery Systems: Challenges and Progress | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/adfm.202402975 | - |
dc.identifier.scopus | eid_2-s2.0-85195698929 | - |
dc.identifier.eissn | 1616-3028 | - |
dc.identifier.issnl | 1616-301X | - |