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Article: AIEgen-caged ultrafast photochemical delivery and visualization of nitric oxide

TitleAIEgen-caged ultrafast photochemical delivery and visualization of nitric oxide
Authors
KeywordsAIE
Cell image
Nitric oxide
Photocage
Issue Date6-Jan-2024
PublisherElsevier
Citation
Sensors and Actuators B: Chemical, 2024, v. 405 How to Cite?
Abstract

The development of bifunctional AIEgens for direct delivering and visualizing bioactive species together remains a great challenge to date. Herein, we fabricated a novel photoactivatable nitric oxide (NO) donor with a built-in AIE fluorophore, which can rapidly release NO and AIEgen upon light irradiation. The ultrafast NO generation can be obtained in 2.1 ps, with the yielding of a greatly drastic fluorescence turn-on AIEgen probe (300,000-fold intensity enhanced). Using this NO donor, real-time cell images of NO-releasing through the emission of AIEgen were successfully achieved through direct excitation of the donor in cells in situ.


Persistent Identifierhttp://hdl.handle.net/10722/344974
ISSN
2023 Impact Factor: 8.0
2023 SCImago Journal Rankings: 1.475

 

DC FieldValueLanguage
dc.contributor.authorShang, Jirui-
dc.contributor.authorCui, Yunxi-
dc.contributor.authorWu, Peixuan-
dc.contributor.authorChi, Weijie-
dc.contributor.authorYu, Peng-
dc.contributor.authorFu, Kun-
dc.contributor.authorPhillips, David Lee-
dc.contributor.authorSun, Zhicheng-
dc.contributor.authorLiu, Yuanyuan-
dc.contributor.authorDu Lili-
dc.contributor.authorZhou, Yang-
dc.date.accessioned2024-08-14T08:56:36Z-
dc.date.available2024-08-14T08:56:36Z-
dc.date.issued2024-01-06-
dc.identifier.citationSensors and Actuators B: Chemical, 2024, v. 405-
dc.identifier.issn0925-4005-
dc.identifier.urihttp://hdl.handle.net/10722/344974-
dc.description.abstract<p>The development of bifunctional AIEgens for direct delivering and visualizing bioactive species together remains a great challenge to date. Herein, we fabricated a novel photoactivatable <a href="https://www.sciencedirect.com/topics/chemical-engineering/nitric-oxide" title="Learn more about nitric oxide from ScienceDirect's AI-generated Topic Pages">nitric oxide</a> (NO) donor with a built-in <a href="https://www.sciencedirect.com/topics/chemistry/aggregation-induced-emission" title="Learn more about AIE from ScienceDirect's AI-generated Topic Pages">AIE</a> <a href="https://www.sciencedirect.com/topics/engineering/fluorophore" title="Learn more about fluorophore from ScienceDirect's AI-generated Topic Pages">fluorophore</a>, which can rapidly <a href="https://www.sciencedirect.com/topics/engineering/nitric-oxide-release" title="Learn more about release NO from ScienceDirect's AI-generated Topic Pages">release NO</a> and AIEgen upon <a href="https://www.sciencedirect.com/topics/chemistry/light-irradiation" title="Learn more about light irradiation from ScienceDirect's AI-generated Topic Pages">light irradiation</a>. The ultrafast <a href="https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nitric-oxide" title="Learn more about NO from ScienceDirect's AI-generated Topic Pages">NO</a> generation can be obtained in 2.1 ps, with the yielding of a greatly drastic fluorescence turn-on AIEgen probe (300,000-fold intensity enhanced). Using this <a href="https://www.sciencedirect.com/topics/chemistry/nitric-oxide" title="Learn more about NO from ScienceDirect's AI-generated Topic Pages">NO</a> donor, real-time cell images of NO-releasing through the emission of AIEgen were successfully achieved through direct excitation of the donor in cells in situ.<br></p>-
dc.languageeng-
dc.publisherElsevier-
dc.relation.ispartofSensors and Actuators B: Chemical-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAIE-
dc.subjectCell image-
dc.subjectNitric oxide-
dc.subjectPhotocage-
dc.titleAIEgen-caged ultrafast photochemical delivery and visualization of nitric oxide-
dc.typeArticle-
dc.identifier.doi10.1016/j.snb.2024.135287-
dc.identifier.scopuseid_2-s2.0-85183111726-
dc.identifier.volume405-
dc.identifier.eissn1944-8201-
dc.identifier.issnl0925-4005-

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