File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1016/j.jdent.2024.104965
- Find via
Supplementary
-
Citations:
- Appears in Collections:
Article: Physical properties and enamel remineralization potential of arginine-fluoride varnishes
Title | Physical properties and enamel remineralization potential of arginine-fluoride varnishes |
---|---|
Authors | |
Issue Date | 26-Mar-2024 |
Publisher | Elsevier |
Citation | Journal of Dentistry, 2024 How to Cite? |
Abstract | ObjectiveThe study objectives were to examine the physical properties and enamel remineralization potential of fluoride (F) varnishes incorporated with arginine (Arg). MethodsFour commercial F varnishes: 1) Duraphat®; 2) Flúor Protector®, 3) Fluor Protector S®, and 4) Fluorimax™ were supplemented with 2% w/v. Arg. The control/experimental varnishes underwent rheometric analysis to assess varnish density (δ), velocity (ν), and associated viscosity, both quantitatively (ν/δ) and qualitatively based on determined mass, volume, distance flow, and time under experimentation. The varnish wet/dry weights (at 2 h) were also analysed. Further, sound enamel specimens (T0) with artificial incipient caries-like lesions (T1) were treated with control/experimental varnishes and subjected to remineralization assay with artificial saliva for 6 h. Thereafter (T2), the specimens were characterized to estimate precipitated Ca and net enamel F uptake. Additionally, mineral density (MD) was assessed using micro-CT at T0, T1, and T2 to derive mineral gain (MG) and % remineralization for the treatment groups. ResultsWhen Arg is incorporated, the physical properties of the F-containing varnishes undergo a significant transformation, resulting in higher density, varnish weight, dry varnish weight, and viscosity compared to their respective control varnishes (p<0.05). Incorporating Arg in Duraphat®, Fluor Protector S®, and Fluorimax™ significantly improved both enamel Ca precipitation and F uptake compared to the respective controls (p<0.05). Additionally, the enamel F uptake was significantly higher with all the tested varnishes when enriched with Arg (p<0.05). The combined data for MD, MG, and % remineralization suggests that the remineralization potential of F-varnishes significantly increased when enriched with Arg (p<0.05). ConclusionIncorporating Arg in inorganic F varnishes improves their physical properties and enhances the enamel remineralization potential of the varnishes. Clinical significanceThis study highlights the possibility of incorporating Arg in distinct F-source varnishes. The synergism between active components (Arg-F) aids in enhanced remineralization and superior varnish physical properties, demonstrating a promising approach for high caries-risk patients. |
Persistent Identifier | http://hdl.handle.net/10722/344201 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.313 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bijle, Mohammed Nadeem | - |
dc.contributor.author | Naseer, Tiba Kahtan | - |
dc.contributor.author | Yiu, Cynthia | - |
dc.date.accessioned | 2024-07-16T03:41:36Z | - |
dc.date.available | 2024-07-16T03:41:36Z | - |
dc.date.issued | 2024-03-26 | - |
dc.identifier.citation | Journal of Dentistry, 2024 | - |
dc.identifier.issn | 0300-5712 | - |
dc.identifier.uri | http://hdl.handle.net/10722/344201 | - |
dc.description.abstract | <h3>Objective</h3><p>The study objectives were to examine the physical properties and enamel remineralization potential of fluoride (F) varnishes incorporated with arginine (Arg).</p><h3>Methods</h3><p>Four commercial F varnishes: 1) Duraphat®; 2) Flúor Protector®, 3) Fluor Protector S®, and 4) Fluorimax™ were supplemented with 2% <em>w/v</em>. Arg. The control/experimental varnishes underwent rheometric analysis to assess varnish density (δ), velocity (ν), and associated viscosity, both quantitatively (ν/δ) and qualitatively based on determined mass, volume, distance flow, and time under experimentation. The varnish wet/dry weights (at 2 h) were also analysed. Further, sound enamel specimens (T0) with artificial incipient caries-like lesions (T1) were treated with control/experimental varnishes and subjected to remineralization assay with artificial saliva for 6 h. Thereafter (T2), the specimens were characterized to estimate precipitated Ca and net enamel F uptake. Additionally, mineral density (MD) was assessed using micro-CT at T0, T1, and T2 to derive mineral gain (MG) and % remineralization for the treatment groups.</p><h3>Results</h3><p>When Arg is incorporated, the physical properties of the F-containing varnishes undergo a significant transformation, resulting in higher density, varnish weight, dry varnish weight, and viscosity compared to their respective control varnishes (p<0.05). Incorporating Arg in Duraphat®, Fluor Protector S®, and Fluorimax™ significantly improved both enamel Ca precipitation and F uptake compared to the respective controls (p<0.05). Additionally, the enamel F uptake was significantly higher with all the tested varnishes when enriched with Arg (p<0.05). The combined data for MD, MG, and % remineralization suggests that the remineralization potential of F-varnishes significantly increased when enriched with Arg (p<0.05).</p><h3>Conclusion</h3><p>Incorporating Arg in inorganic F varnishes improves their physical properties and enhances the enamel remineralization potential of the varnishes.</p><h3>Clinical significance</h3><p>This study highlights the possibility of incorporating Arg in distinct F-source varnishes. The synergism between active components (Arg-F) aids in enhanced remineralization and superior varnish physical properties, demonstrating a promising approach for high caries-risk patients.</p> | - |
dc.language | eng | - |
dc.publisher | Elsevier | - |
dc.relation.ispartof | Journal of Dentistry | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | Physical properties and enamel remineralization potential of arginine-fluoride varnishes | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jdent.2024.104965 | - |
dc.identifier.issnl | 0300-5712 | - |