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Article: Ten years' research on a cardiovascular tonic: A comprehensive approach - From quality control and mechanisms of action to clinical trial
Title | Ten years' research on a cardiovascular tonic: A comprehensive approach - From quality control and mechanisms of action to clinical trial |
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Authors | |
Issue Date | 2013 |
Citation | Evidence-based Complementary and Alternative Medicine, 2013, v. 2013, article no. 319703 How to Cite? |
Abstract | Objective. Mortality arising from cardiovascular pathologies remains one of the highest. Maintenance of cardiovascular health therefore remains a universal concern. Interventional therapies and medications have made impressive advances, but preventive measures would be of the same importance. Method. Ten years' search for a simple herbal formula has resulted in a two-herb combination, consisting of Salviae Miltiorrhizae Radix et Rhizoma and Puerariae Lobatae Radix. The formula has been studied extensively on cardiovascular biological platforms and then put on three clinical trials. Results. In the laboratory, the formula was found to have the biological effects of anti-inflammation, anti-oxidation, anti-foam cell formation on vascular endothelium, and vasodilation. Clinical trials using ultrasonic carotid intima thickness as a surrogate marker showed very significant benefits. No significant adverse effects were encountered. Conclusion. It is therefore recommended that the herbal formula could be used as an adjuvant therapy in cardiac patients under treatment or as a preventive agent among the susceptible. © 2013 Ping-Chung Leung et al. |
Persistent Identifier | http://hdl.handle.net/10722/343141 |
ISSN | 2021 Impact Factor: 2.650 |
DC Field | Value | Language |
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dc.contributor.author | Leung, Ping Chung | - |
dc.contributor.author | Koon, Chi Man | - |
dc.contributor.author | Lau, Clara Bik San | - |
dc.contributor.author | Chook, Ping | - |
dc.contributor.author | Cheng, William King Fai | - |
dc.contributor.author | Fung, Kwok Pui | - |
dc.contributor.author | Kwok, Timothy Chi Yui | - |
dc.contributor.author | Woo, Kam Sang | - |
dc.date.accessioned | 2024-05-10T09:05:47Z | - |
dc.date.available | 2024-05-10T09:05:47Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Evidence-based Complementary and Alternative Medicine, 2013, v. 2013, article no. 319703 | - |
dc.identifier.issn | 1741-427X | - |
dc.identifier.uri | http://hdl.handle.net/10722/343141 | - |
dc.description.abstract | Objective. Mortality arising from cardiovascular pathologies remains one of the highest. Maintenance of cardiovascular health therefore remains a universal concern. Interventional therapies and medications have made impressive advances, but preventive measures would be of the same importance. Method. Ten years' search for a simple herbal formula has resulted in a two-herb combination, consisting of Salviae Miltiorrhizae Radix et Rhizoma and Puerariae Lobatae Radix. The formula has been studied extensively on cardiovascular biological platforms and then put on three clinical trials. Results. In the laboratory, the formula was found to have the biological effects of anti-inflammation, anti-oxidation, anti-foam cell formation on vascular endothelium, and vasodilation. Clinical trials using ultrasonic carotid intima thickness as a surrogate marker showed very significant benefits. No significant adverse effects were encountered. Conclusion. It is therefore recommended that the herbal formula could be used as an adjuvant therapy in cardiac patients under treatment or as a preventive agent among the susceptible. © 2013 Ping-Chung Leung et al. | - |
dc.language | eng | - |
dc.relation.ispartof | Evidence-based Complementary and Alternative Medicine | - |
dc.title | Ten years' research on a cardiovascular tonic: A comprehensive approach - From quality control and mechanisms of action to clinical trial | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1155/2013/319703 | - |
dc.identifier.scopus | eid_2-s2.0-84890085620 | - |
dc.identifier.volume | 2013 | - |
dc.identifier.spage | article no. 319703 | - |
dc.identifier.epage | article no. 319703 | - |
dc.identifier.eissn | 1741-4288 | - |