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Article: Anti-allergic drug discovery in China for eczema: Current methods and future strategies

TitleAnti-allergic drug discovery in China for eczema: Current methods and future strategies
Authors
KeywordsAllergy
Atopic dermatitis
Eczema
Herbal medicine
Traditional Chinese medicine
Issue Date2013
Citation
Expert Opinion on Drug Discovery, 2013, v. 8, n. 7, p. 753-767 How to Cite?
AbstractIntroduction: Eczema is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for this disease, treatment relies on topical and systemic anti-allergic or immunomodulating therapies. Topical corticosteroids, macrolide immunosuppressants and oral immunomodulating drugs have been the mainstay for the treatment of recalcitrant disease. However, in China as well as throughout Asia, the use of traditional and proprietary topical and herbal medicines is also popular. Areas covered: This article reviews the evidence for the anti-allergic effects of topical and oral forms of these medicinal. The authors also present and discuss the current methods of preparation and evaluation for these traditional and proprietary medications. Additionally, the authors present the novel delivery method of employing nanotechnology to deliver these herbal therapies. Expert opinion: Many herbal concoctions have had trials which have claimed therapeutic benefits for eczema. However, the scientific methods in these trials are often flawed and often not objective. In fact, the majority of these trials do not provide proof of objective efficacy for the anti-allergic effects claimed. It is felt that the delivery of herbal medication by nanotechnology has several crucial challenges that certainly need to be overcome for the optimal design of therapies for eczema, through optimizing material properties, methods of delivery and understanding the mechanisms of action. © 2013 Informa UK, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/343122
ISSN
2023 Impact Factor: 6.0
2023 SCImago Journal Rankings: 1.077

 

DC FieldValueLanguage
dc.contributor.authorHon, Kam Lun-
dc.contributor.authorLau, Clara Bik San-
dc.contributor.authorHui, Patrick Chi Leung-
dc.contributor.authorLeung, Ping Chung-
dc.date.accessioned2024-05-10T09:05:37Z-
dc.date.available2024-05-10T09:05:37Z-
dc.date.issued2013-
dc.identifier.citationExpert Opinion on Drug Discovery, 2013, v. 8, n. 7, p. 753-767-
dc.identifier.issn1746-0441-
dc.identifier.urihttp://hdl.handle.net/10722/343122-
dc.description.abstractIntroduction: Eczema is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for this disease, treatment relies on topical and systemic anti-allergic or immunomodulating therapies. Topical corticosteroids, macrolide immunosuppressants and oral immunomodulating drugs have been the mainstay for the treatment of recalcitrant disease. However, in China as well as throughout Asia, the use of traditional and proprietary topical and herbal medicines is also popular. Areas covered: This article reviews the evidence for the anti-allergic effects of topical and oral forms of these medicinal. The authors also present and discuss the current methods of preparation and evaluation for these traditional and proprietary medications. Additionally, the authors present the novel delivery method of employing nanotechnology to deliver these herbal therapies. Expert opinion: Many herbal concoctions have had trials which have claimed therapeutic benefits for eczema. However, the scientific methods in these trials are often flawed and often not objective. In fact, the majority of these trials do not provide proof of objective efficacy for the anti-allergic effects claimed. It is felt that the delivery of herbal medication by nanotechnology has several crucial challenges that certainly need to be overcome for the optimal design of therapies for eczema, through optimizing material properties, methods of delivery and understanding the mechanisms of action. © 2013 Informa UK, Ltd.-
dc.languageeng-
dc.relation.ispartofExpert Opinion on Drug Discovery-
dc.subjectAllergy-
dc.subjectAtopic dermatitis-
dc.subjectEczema-
dc.subjectHerbal medicine-
dc.subjectTraditional Chinese medicine-
dc.titleAnti-allergic drug discovery in China for eczema: Current methods and future strategies-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1517/17460441.2013.795539-
dc.identifier.pmid23642103-
dc.identifier.scopuseid_2-s2.0-84879365035-
dc.identifier.volume8-
dc.identifier.issue7-
dc.identifier.spage753-
dc.identifier.epage767-
dc.identifier.eissn1746-045X-

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