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- Publisher Website: 10.1038/clpt.2013.157
- Scopus: eid_2-s2.0-84886727251
- PMID: 23933971
- WOS: WOS:000326090100019
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Article: Cometabolism of microbes and host: Implications for drug metabolism and drug-induced toxicity
Title | Cometabolism of microbes and host: Implications for drug metabolism and drug-induced toxicity |
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Authors | |
Issue Date | 2013 |
Citation | Clinical Pharmacology and Therapeutics, 2013, v. 94, n. 5, p. 574-581 How to Cite? |
Abstract | The recognition of the gut microbial-mammalian metabolic axis and its implications in human metabolic disease opens a new window to understanding the contribution of the gut microbiome to drug metabolism and drug-induced toxicity. The integrative omics approaches, including pharmacometabonomics and metagenomics, have demonstrated great promise for characterizing xenobiotic interventions that are associated with wide variation in efficacy or toxicity in humans, as well as for predicting individual response and susceptibility to toxicity. © 2013 American Society for Clinical Pharmacology and Therapeutics. |
Persistent Identifier | http://hdl.handle.net/10722/342461 |
ISSN | 2023 Impact Factor: 6.3 2023 SCImago Journal Rankings: 1.988 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, H. | - |
dc.contributor.author | Jia, W. | - |
dc.date.accessioned | 2024-04-17T07:03:59Z | - |
dc.date.available | 2024-04-17T07:03:59Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Clinical Pharmacology and Therapeutics, 2013, v. 94, n. 5, p. 574-581 | - |
dc.identifier.issn | 0009-9236 | - |
dc.identifier.uri | http://hdl.handle.net/10722/342461 | - |
dc.description.abstract | The recognition of the gut microbial-mammalian metabolic axis and its implications in human metabolic disease opens a new window to understanding the contribution of the gut microbiome to drug metabolism and drug-induced toxicity. The integrative omics approaches, including pharmacometabonomics and metagenomics, have demonstrated great promise for characterizing xenobiotic interventions that are associated with wide variation in efficacy or toxicity in humans, as well as for predicting individual response and susceptibility to toxicity. © 2013 American Society for Clinical Pharmacology and Therapeutics. | - |
dc.language | eng | - |
dc.relation.ispartof | Clinical Pharmacology and Therapeutics | - |
dc.title | Cometabolism of microbes and host: Implications for drug metabolism and drug-induced toxicity | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1038/clpt.2013.157 | - |
dc.identifier.pmid | 23933971 | - |
dc.identifier.scopus | eid_2-s2.0-84886727251 | - |
dc.identifier.volume | 94 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 574 | - |
dc.identifier.epage | 581 | - |
dc.identifier.eissn | 1532-6535 | - |
dc.identifier.isi | WOS:000326090100019 | - |