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Article: Metabolite profiling of Panax notoginseng using UPLC-ESI-MS

TitleMetabolite profiling of Panax notoginseng using UPLC-ESI-MS
Authors
KeywordsElectrospray ionization (ESI)
Metabolite profiling
Multivariate statistical analysis
Panax notoginseng
Quadrupole time-of-flight mass spectrometer (QtofMS)
Saponin
Ultra-performance liquid chromatography (UPLC)
Issue Date2008
Citation
Phytochemistry, 2008, v. 69, n. 11, p. 2237-2244 How to Cite?
AbstractThe metabolite profiling of different parts of Panax notoginseng was carried out using rapid ultra-performance liquid chromatography-electrospray ionization mass spectrometry (UPLC-ESI-MS) and multivariate statistical analysis. Principal component analysis (PCA) of the UPLC-ESI-MS data showed a clear separation of compositions among the flower buds, roots and rhizomes of P. notoginseng. The saponins accounting for such variations were identified through the corresponding loadings weights and were further verified by accurate mass, tandem mass and retention times of available standard saponins using UPLC quadrupole time-of-flight mass spectrometer (UPLC-QtofMS). Finally, the influential factors of different metabolic phenotypes of P. notoginseng was elucidated. The currently proposed UPLC-ESI-MS/MS analytical method coupled with multivariate statistical analysis can be further utilized to evaluate chemical components obtained from different parts of the plant and/or the plant of different geographical locations, thereby classifying the medicinal plant resources and potentially elucidating the mechanism of inherent phytochemical diversity. © 2008 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/342329
ISSN
2023 Impact Factor: 3.2
2023 SCImago Journal Rankings: 0.667
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDan, Mo-
dc.contributor.authorSu, Mingming-
dc.contributor.authorGao, Xianfu-
dc.contributor.authorZhao, Tie-
dc.contributor.authorZhao, Aihua-
dc.contributor.authorXie, Guoxiang-
dc.contributor.authorQiu, Yunping-
dc.contributor.authorZhou, Mingmei-
dc.contributor.authorLiu, Zhong-
dc.contributor.authorJia, Wei-
dc.date.accessioned2024-04-17T07:03:01Z-
dc.date.available2024-04-17T07:03:01Z-
dc.date.issued2008-
dc.identifier.citationPhytochemistry, 2008, v. 69, n. 11, p. 2237-2244-
dc.identifier.issn0031-9422-
dc.identifier.urihttp://hdl.handle.net/10722/342329-
dc.description.abstractThe metabolite profiling of different parts of Panax notoginseng was carried out using rapid ultra-performance liquid chromatography-electrospray ionization mass spectrometry (UPLC-ESI-MS) and multivariate statistical analysis. Principal component analysis (PCA) of the UPLC-ESI-MS data showed a clear separation of compositions among the flower buds, roots and rhizomes of P. notoginseng. The saponins accounting for such variations were identified through the corresponding loadings weights and were further verified by accurate mass, tandem mass and retention times of available standard saponins using UPLC quadrupole time-of-flight mass spectrometer (UPLC-QtofMS). Finally, the influential factors of different metabolic phenotypes of P. notoginseng was elucidated. The currently proposed UPLC-ESI-MS/MS analytical method coupled with multivariate statistical analysis can be further utilized to evaluate chemical components obtained from different parts of the plant and/or the plant of different geographical locations, thereby classifying the medicinal plant resources and potentially elucidating the mechanism of inherent phytochemical diversity. © 2008 Elsevier Ltd. All rights reserved.-
dc.languageeng-
dc.relation.ispartofPhytochemistry-
dc.subjectElectrospray ionization (ESI)-
dc.subjectMetabolite profiling-
dc.subjectMultivariate statistical analysis-
dc.subjectPanax notoginseng-
dc.subjectQuadrupole time-of-flight mass spectrometer (QtofMS)-
dc.subjectSaponin-
dc.subjectUltra-performance liquid chromatography (UPLC)-
dc.titleMetabolite profiling of Panax notoginseng using UPLC-ESI-MS-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.phytochem.2008.04.015-
dc.identifier.pmid18550132-
dc.identifier.scopuseid_2-s2.0-48049107321-
dc.identifier.volume69-
dc.identifier.issue11-
dc.identifier.spage2237-
dc.identifier.epage2244-
dc.identifier.isiWOS:000258863100021-

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