Chemical constituents of antihyperglycemic active fraction from Arctium lappa

Abstract

Aim: To investigate the bioactive compounds from Arctium lappa. Methods: The compounds were obtained by various chromatographic methods including silica gel and sephadex LH-20 and their structures were elucidated on the basis of physical parameters and spectral data including IR, UV, NMR and MS. Result: Eight compounds were determined as matairesinol (I), arctigenin (II), lappaol A (III), lappaol F (IV), lappaol C (V), arctignan E (VI), arctiin (VII) and lappaol H (VIII). Conclusion: All the compounds from the active fraction of Arctium lappa are lignans which might be associated with its hypoglycemic activities.