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Article: Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India

TitleModeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India
Authors
Issue Date1-May-2022
PublisherSpringer
Citation
Journal of Natural Medicines, 2022, v. 28, n. 5, p. 934-938 How to Cite?
Abstract

Given global Coronavirus Disease 2019 (COVID-19) vaccine shortages and inequity of vaccine distributions, fractionation of vaccine doses might be an effective strategy for reducing public health and economic burden, notwithstanding the emergence of new variants of concern. In this study, we developed a multi-scale model incorporating population-level transmission and individual-level vaccination to estimate the costs of hospitalization and vaccination and the economic benefits of reducing COVID-19 deaths due to dose-fractionation strategies in India. We used large-scale survey data of the willingness to pay together with data of vaccine and hospital admission costs to build the model. We found that fractional doses of vaccines could be an economically viable vaccination strategy compared to alternatives of either full-dose vaccination or no vaccination. Dose-sparing strategies could save a large number of lives, even with the emergence of new variants with higher transmissibility.


Persistent Identifierhttp://hdl.handle.net/10722/342151
ISSN
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.685
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDu, Zhanwei-
dc.contributor.authorWang, Lin-
dc.contributor.authorPandey, Abhishek-
dc.contributor.authorLim, Wey Wen-
dc.contributor.authorChinazzi, Matteo-
dc.contributor.authorPiontti, Ana Pastore Y-
dc.contributor.authorLau, Eric H Y-
dc.contributor.authorWu, Peng-
dc.contributor.authorMalani, Anup-
dc.contributor.authorCobey, Sarah-
dc.contributor.authorCowling, Benjamin J-
dc.date.accessioned2024-04-17T03:49:37Z-
dc.date.available2024-04-17T03:49:37Z-
dc.date.issued2022-05-01-
dc.identifier.citationJournal of Natural Medicines, 2022, v. 28, n. 5, p. 934-938-
dc.identifier.issn1340-3443-
dc.identifier.urihttp://hdl.handle.net/10722/342151-
dc.description.abstract<p>Given global Coronavirus Disease 2019 (COVID-19) vaccine shortages and inequity of vaccine distributions, fractionation of vaccine doses might be an effective strategy for reducing public health and economic burden, notwithstanding the emergence of new variants of concern. In this study, we developed a multi-scale model incorporating population-level transmission and individual-level vaccination to estimate the costs of hospitalization and vaccination and the economic benefits of reducing COVID-19 deaths due to dose-fractionation strategies in India. We used large-scale survey data of the willingness to pay together with data of vaccine and hospital admission costs to build the model. We found that fractional doses of vaccines could be an economically viable vaccination strategy compared to alternatives of either full-dose vaccination or no vaccination. Dose-sparing strategies could save a large number of lives, even with the emergence of new variants with higher transmissibility.</p>-
dc.languageeng-
dc.publisherSpringer-
dc.relation.ispartofJournal of Natural Medicines-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleModeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India-
dc.typeArticle-
dc.identifier.doi10.1038/s41591-022-01736-z-
dc.identifier.scopuseid_2-s2.0-85125144562-
dc.identifier.volume28-
dc.identifier.issue5-
dc.identifier.spage934-
dc.identifier.epage938-
dc.identifier.eissn1861-0293-
dc.identifier.isiWOS:000761879000003-
dc.identifier.issnl1340-3443-

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