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Article: Metal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide

TitleMetal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide
Authors
James, D. MartinWintner, EdwardFaulkner, D. JohnSiegel, Jay S.
Issue Date1993
Citation
Heterocycles, 1993, v. 35, n. 2, p. 675-678 How to Cite?
DOI: http://dx.doi.org/10.3987/com-92-s(t)122
AbstractMetal binding to the oxazole portion of dihydrohalichondramide (1), trisoxazole (2), and diphenyloxazole (3) are studied by fluorescence quenching and nmr techniques. The trisoxazole conformation is modeled by semiempirical computations. 1-3 are found to be relatively weak binders which do not exhibit a significant chelate effect. The biological action of 1 is not related to metal binding. © 1993.
Persistent Identifierhttp://hdl.handle.net/10722/341440
ISSN
0385-5414
2023 Impact Factor: 0.8
2023 SCImago Journal Rankings: 0.172

 

DC FieldValueLanguage
dc.contributor.authorJames, D. Martin-
dc.contributor.authorWintner, Edward-
dc.contributor.authorFaulkner, D. John-
dc.contributor.authorSiegel, Jay S.-
dc.date.accessioned2024-03-13T08:42:50Z-
dc.date.available2024-03-13T08:42:50Z-
dc.date.issued1993-
dc.identifier.citationHeterocycles, 1993, v. 35, n. 2, p. 675-678-
dc.identifier.issn0385-5414-
dc.identifier.urihttp://hdl.handle.net/10722/341440-
dc.description.abstractMetal binding to the oxazole portion of dihydrohalichondramide (1), trisoxazole (2), and diphenyloxazole (3) are studied by fluorescence quenching and nmr techniques. The trisoxazole conformation is modeled by semiempirical computations. 1-3 are found to be relatively weak binders which do not exhibit a significant chelate effect. The biological action of 1 is not related to metal binding. © 1993.-
dc.languageeng-
dc.relation.ispartofHeterocycles-
dc.titleMetal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3987/com-92-s(t)122-
dc.identifier.scopuseid_2-s2.0-0000882086-
dc.identifier.volume35-
dc.identifier.issue2-
dc.identifier.spage675-
dc.identifier.epage678-

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