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Article: Metal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide
Title | Metal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide |
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Authors | |
Issue Date | 1993 |
Citation | Heterocycles, 1993, v. 35, n. 2, p. 675-678 How to Cite? |
Abstract | Metal binding to the oxazole portion of dihydrohalichondramide (1), trisoxazole (2), and diphenyloxazole (3) are studied by fluorescence quenching and nmr techniques. The trisoxazole conformation is modeled by semiempirical computations. 1-3 are found to be relatively weak binders which do not exhibit a significant chelate effect. The biological action of 1 is not related to metal binding. © 1993. |
Persistent Identifier | http://hdl.handle.net/10722/341440 |
ISSN | 2023 Impact Factor: 0.8 2023 SCImago Journal Rankings: 0.172 |
DC Field | Value | Language |
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dc.contributor.author | James, D. Martin | - |
dc.contributor.author | Wintner, Edward | - |
dc.contributor.author | Faulkner, D. John | - |
dc.contributor.author | Siegel, Jay S. | - |
dc.date.accessioned | 2024-03-13T08:42:50Z | - |
dc.date.available | 2024-03-13T08:42:50Z | - |
dc.date.issued | 1993 | - |
dc.identifier.citation | Heterocycles, 1993, v. 35, n. 2, p. 675-678 | - |
dc.identifier.issn | 0385-5414 | - |
dc.identifier.uri | http://hdl.handle.net/10722/341440 | - |
dc.description.abstract | Metal binding to the oxazole portion of dihydrohalichondramide (1), trisoxazole (2), and diphenyloxazole (3) are studied by fluorescence quenching and nmr techniques. The trisoxazole conformation is modeled by semiempirical computations. 1-3 are found to be relatively weak binders which do not exhibit a significant chelate effect. The biological action of 1 is not related to metal binding. © 1993. | - |
dc.language | eng | - |
dc.relation.ispartof | Heterocycles | - |
dc.title | Metal binding by the trisoxazole portion of the marine natural product dihydrohalichondramide | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.3987/com-92-s(t)122 | - |
dc.identifier.scopus | eid_2-s2.0-0000882086 | - |
dc.identifier.volume | 35 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 675 | - |
dc.identifier.epage | 678 | - |