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Article: Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes

TitleMetavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes
Authors
Issue Date5-Jan-2023
PublisherNature Research
Citation
Nature Microbiology, 2023, v. 8, n. 1, p. 162-173 How to Cite?
AbstractThe increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate more ancient divergence than other arboviruses. Tick-specific viruses are often associated with only a few tick species, whereas virus clades that can infect vertebrates are found in a wider range of tick species. We hypothesize that tick viruses can exhibit both ‘specialist’ and ‘generalist’ evolutionary trends. We hope that our virome dataset will enable much-needed research on vertebrate-pathogenic tick-associated viruses.
Persistent Identifierhttp://hdl.handle.net/10722/340567
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNi, XB-
dc.contributor.authorCui, XM-
dc.contributor.authorLiu, JY-
dc.contributor.authorYe, RZ-
dc.contributor.authorWu, YQ-
dc.contributor.authorJiang, JF-
dc.contributor.authorSun, Y-
dc.contributor.authorWang, Q-
dc.contributor.authorShum, MHH-
dc.contributor.authorChang, QC-
dc.contributor.authorZhao, L-
dc.contributor.authorHan, XH-
dc.contributor.authorMa, K-
dc.contributor.authorShen, SJ-
dc.contributor.authorZhang, MZ-
dc.contributor.authorGuo, WB-
dc.contributor.authorZhu, JG-
dc.contributor.authorZhan, L-
dc.contributor.authorLi, LJ-
dc.contributor.authorDing, SJ-
dc.contributor.authorZhu, DY-
dc.contributor.authorZhang, J-
dc.contributor.authorXia, LY-
dc.contributor.authorOong, XY-
dc.contributor.authorRuan, XD-
dc.contributor.authorShao, HZ-
dc.contributor.authorQue, TC-
dc.contributor.authorLiu, GY-
dc.contributor.authorDu CH,-
dc.contributor.authorHuang, EJ-
dc.contributor.authorWang, X-
dc.contributor.authorDu LF,-
dc.contributor.authorWang, CC-
dc.contributor.authorShi, WQ-
dc.contributor.authorPan, YS-
dc.contributor.authorZhou, YH-
dc.contributor.authorQu, JL-
dc.contributor.authorMa, J-
dc.contributor.authorGong, CW-
dc.contributor.authorChen, QQ-
dc.contributor.authorQin, Q-
dc.contributor.authorLam, TTY-
dc.contributor.authorJia, N-
dc.contributor.authorCao, WC-
dc.date.accessioned2024-03-11T10:45:33Z-
dc.date.available2024-03-11T10:45:33Z-
dc.date.issued2023-01-05-
dc.identifier.citationNature Microbiology, 2023, v. 8, n. 1, p. 162-173-
dc.identifier.urihttp://hdl.handle.net/10722/340567-
dc.description.abstractThe increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate more ancient divergence than other arboviruses. Tick-specific viruses are often associated with only a few tick species, whereas virus clades that can infect vertebrates are found in a wider range of tick species. We hypothesize that tick viruses can exhibit both ‘specialist’ and ‘generalist’ evolutionary trends. We hope that our virome dataset will enable much-needed research on vertebrate-pathogenic tick-associated viruses.-
dc.languageeng-
dc.publisherNature Research-
dc.relation.ispartofNature Microbiology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleMetavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes-
dc.typeArticle-
dc.identifier.doi10.1038/s41564-022-01275-w-
dc.identifier.scopuseid_2-s2.0-85145645750-
dc.identifier.volume8-
dc.identifier.issue1-
dc.identifier.spage162-
dc.identifier.epage173-
dc.identifier.eissn2058-5276-
dc.identifier.isiWOS:001006038500001-
dc.identifier.issnl2058-5276-

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