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Article: Investigation of the Impact of Childhood Immune Imprinting on Birth Year-Specific Risk of Clinical Infection During Influenza A Virus Epidemics in Hong Kong

TitleInvestigation of the Impact of Childhood Immune Imprinting on Birth Year-Specific Risk of Clinical Infection During Influenza A Virus Epidemics in Hong Kong
Authors
Tsang, TKGostic, KMChen, SJWang, YFArevalo, PLau, EHYCobey, SCowling, BJ
Keywordsimprinting protection
influenza
surveillance
Issue Date14-Jul-2023
PublisherElsevier
Citation
International Journal of Infectious Diseases, 2023, v. 228, n. 2, p. 169-172 How to Cite?
DOI: http://dx.doi.org/10.1093/infdis/jiad009
Abstract

Influenza imprinting reduces risks of influenza A virus clinical infection by 40%–90%, estimated from surveillance data in western countries. We analyzed surveillance data from 2010 to 2019 in Hong Kong. Based on the best model, which included hemagglutinin group-level imprinting, we estimated that individuals imprinted to H1N1 or H2N2 had a 17% (95% confidence interval [CI], 3%–28%) lower risk of H1N1 clinical infection, and individuals imprinted to H3N2 would have 12% (95% CI, −3% to 26%) lower risk of H3N2 clinical infection. These estimated imprinting protections were weaker than estimates in western countries. Identifying factors affecting imprinting protections is important for control policies and disease modeling.


Persistent Identifierhttp://hdl.handle.net/10722/339922
ISSN
1201-9712
2023 Impact Factor: 4.8
2023 SCImago Journal Rankings: 1.435
ISI Accession Number ID
WOS:000919726800001

 

DC FieldValueLanguage
dc.contributor.authorTsang, TK-
dc.contributor.authorGostic, KM-
dc.contributor.authorChen, SJ-
dc.contributor.authorWang, YF-
dc.contributor.authorArevalo, P-
dc.contributor.authorLau, EHY-
dc.contributor.authorCobey, S-
dc.contributor.authorCowling, BJ-
dc.date.accessioned2024-03-11T10:40:20Z-
dc.date.available2024-03-11T10:40:20Z-
dc.date.issued2023-07-14-
dc.identifier.citationInternational Journal of Infectious Diseases, 2023, v. 228, n. 2, p. 169-172-
dc.identifier.issn1201-9712-
dc.identifier.urihttp://hdl.handle.net/10722/339922-
dc.description.abstract<p>Influenza imprinting reduces risks of influenza A virus clinical infection by 40%–90%, estimated from surveillance data in western countries. We analyzed surveillance data from 2010 to 2019 in Hong Kong. Based on the best model, which included hemagglutinin group-level imprinting, we estimated that individuals imprinted to H1N1 or H2N2 had a 17% (95% confidence interval [CI], 3%–28%) lower risk of H1N1 clinical infection, and individuals imprinted to H3N2 would have 12% (95% CI, −3% to 26%) lower risk of H3N2 clinical infection. These estimated imprinting protections were weaker than estimates in western countries. Identifying factors affecting imprinting protections is important for control policies and disease modeling.</p>-
dc.languageeng-
dc.publisherElsevier-
dc.relation.ispartofInternational Journal of Infectious Diseases-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectimprinting protection-
dc.subjectinfluenza-
dc.subjectsurveillance-
dc.titleInvestigation of the Impact of Childhood Immune Imprinting on Birth Year-Specific Risk of Clinical Infection During Influenza A Virus Epidemics in Hong Kong-
dc.typeArticle-
dc.identifier.doi10.1093/infdis/jiad009-
dc.identifier.scopuseid_2-s2.0-85164845989-
dc.identifier.volume228-
dc.identifier.issue2-
dc.identifier.spage169-
dc.identifier.epage172-
dc.identifier.isiWOS:000919726800001-
dc.identifier.issnl1201-9712-

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