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Conference Paper: Vocal fold augmentation reduces pneumonia incidence in patients with iatrogenic recurrent laryngeal nerve palsy after esophagectomy (Oral Presentation)

TitleVocal fold augmentation reduces pneumonia incidence in patients with iatrogenic recurrent laryngeal nerve palsy after esophagectomy (Oral Presentation)
Authors
Issue Date30-Aug-2023
PublisherOxford University Press
Abstract

Background

Recurrent laryngeal nerve (RLN) palsy is a significant complication associated with esophagectomy, resulting in a high incidence of pneumonia and a poor quality of life. Vocal fold augmentation (VFA) can help alleviate the associated symptoms of dysphonia. We aimed to investigate the impact of VFA on pneumonia incidence in patients suffering from RLN palsy after esophagectomy.

Methods

This is a retrospective cohort study. Patients who underwent esophagectomy at our center from 2003 to 2022, and experienced right, left or bilateral RLN palsy postoperatively were selected from a prospectively managed database. VFA consisted of medialisation thyroplasty, injection laryngoplasty, arytenoid adduction or a combination of these procedures. Pneumonia was defined as lung changes on chest x-ray, along with clinical evidence of infection within six months after esophagectomy. Pearson’s chi-squared test was used to assess the difference in pneumonia rates. Univariate and multivariate logistic regression analyses were used to identify associations between variables and the outcome of pneumonia.

Results

A total of 107 esophagectomy patients with RLN palsy were included. The overall palsy rate was 14.5%. 41 patients (38.3%) underwent VFA. Of the patients who underwent VFA, 13 (31.7%) underwent medialization thyroplasty, 26 (63.4%) underwent injection laryngoplasty, 1 (2.4%) underwent injection laryngoplasty and medialization thyroplasty, and 1 (2.4%) underwent injection laryngoplasty and arytenoid adduction. Pneumonia rate (14.6%) for patients who underwent VFA was significantly lower than that of patients without VFA (47.0%, P < 0.001). On univariate and multivariate analyses, patients who underwent VFA were less likely to suffer from pneumonia compared to those without VFA (OR = 0.194, P = 0.001).

Conclusion

Vocal fold augmentation reduces pneumonia incidence in patients with recurrent laryngeal nerve palsy after esophagectomy.


Persistent Identifierhttp://hdl.handle.net/10722/338532
ISSN
2023 Impact Factor: 2.3
2023 SCImago Journal Rankings: 1.038

 

DC FieldValueLanguage
dc.contributor.authorLi, R-
dc.contributor.authorWong, IYH-
dc.contributor.authorZhang, R-
dc.contributor.authorWong, CLY-
dc.contributor.authorChan, KK-
dc.contributor.authorLaw, TT-
dc.contributor.authorChan, SY-
dc.contributor.authorLaw, SYK-
dc.date.accessioned2024-03-11T10:29:36Z-
dc.date.available2024-03-11T10:29:36Z-
dc.date.issued2023-08-30-
dc.identifier.issn1120-8694-
dc.identifier.urihttp://hdl.handle.net/10722/338532-
dc.description.abstract<p>Background</p><p>Recurrent laryngeal nerve (RLN) palsy is a significant complication associated with esophagectomy, resulting in a high incidence of pneumonia and a poor quality of life. Vocal fold augmentation (VFA) can help alleviate the associated symptoms of dysphonia. We aimed to investigate the impact of VFA on pneumonia incidence in patients suffering from RLN palsy after esophagectomy.</p><p>Methods</p><p>This is a retrospective cohort study. Patients who underwent esophagectomy at our center from 2003 to 2022, and experienced right, left or bilateral RLN palsy postoperatively were selected from a prospectively managed database. VFA consisted of medialisation thyroplasty, injection laryngoplasty, arytenoid adduction or a combination of these procedures. Pneumonia was defined as lung changes on chest x-ray, along with clinical evidence of infection within six months after esophagectomy. Pearson’s chi-squared test was used to assess the difference in pneumonia rates. Univariate and multivariate logistic regression analyses were used to identify associations between variables and the outcome of pneumonia.</p><p>Results</p><p>A total of 107 esophagectomy patients with RLN palsy were included. The overall palsy rate was 14.5%. 41 patients (38.3%) underwent VFA. Of the patients who underwent VFA, 13 (31.7%) underwent medialization thyroplasty, 26 (63.4%) underwent injection laryngoplasty, 1 (2.4%) underwent injection laryngoplasty and medialization thyroplasty, and 1 (2.4%) underwent injection laryngoplasty and arytenoid adduction. Pneumonia rate (14.6%) for patients who underwent VFA was significantly lower than that of patients without VFA (47.0%, P < 0.001). On univariate and multivariate analyses, patients who underwent VFA were less likely to suffer from pneumonia compared to those without VFA (OR = 0.194, P = 0.001).</p><p>Conclusion</p><p>Vocal fold augmentation reduces pneumonia incidence in patients with recurrent laryngeal nerve palsy after esophagectomy.</p>-
dc.languageeng-
dc.publisherOxford University Press-
dc.relation.ispartofDiseases of the Esophagus-
dc.titleVocal fold augmentation reduces pneumonia incidence in patients with iatrogenic recurrent laryngeal nerve palsy after esophagectomy (Oral Presentation)-
dc.typeConference_Paper-
dc.identifier.doi10.1093/dote.doad052.235-
dc.identifier.volume36-
dc.identifier.issueSupplement 2-
dc.identifier.spage79-
dc.identifier.epage79-
dc.identifier.eissn1442-2050-
dc.identifier.issnl1120-8694-

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