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Article: Association between BNT162b2 and CoronaVac vaccination and risk of CVD and mortality after COVID-19 infection: A population-based cohort study

TitleAssociation between BNT162b2 and CoronaVac vaccination and risk of CVD and mortality after COVID-19 infection: A population-based cohort study
Authors
Keywordsinactivated vaccine
incident CVD
long COVID
omicron
post-COVID CVD
SARS-CoV-2
Issue Date22-Aug-2023
PublisherCell Press
Citation
Cell Reports Medicine, 2023, v. 4, n. 10 How to Cite?
Abstract

It is unknown if vaccination affects the risk of post-COVID-19 cardiovascular diseases (CVDs). Therefore, this retrospective cohort study examines the short-term and long-term risks of post-infection CVD among COVID-19 patients with different vaccination status utilizing data from electronic health databases in Hong Kong. Cox proportional hazards regression adjusted with inverse probability of treatment weighting is used to evaluate the risks of incident CVD (coronary heart disease, stroke, heart failure) and all-cause mortality in COVID-19 patients. Compared with unvaccinated patients, vaccinated patients have a lower risk of CVD and all-cause mortality, and the lowest risk is observed in those who completed three doses of vaccine. Similar patterns in the subgroups of different vaccine platforms, age, gender, Charlson comorbidity index, and disease severity are observed. These findings highlight a positive dose-response relationship between overall CVD risk reduction and the number of vaccine doses received.


Persistent Identifierhttp://hdl.handle.net/10722/337474
ISSN
2023 Impact Factor: 11.7
2023 SCImago Journal Rankings: 4.276
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWan, Eric Yuk Fai-
dc.contributor.authorMok, Anna Hoi Ying-
dc.contributor.authorYan, Vincent Ka Chun-
dc.contributor.authorChan, Cheyenne I Ying-
dc.contributor.authorWang, Boyuan-
dc.contributor.authorLai, Francisco Tsz Tsun-
dc.contributor.authorChui, Celine Sze Ling-
dc.contributor.authorLi, Xue-
dc.contributor.authorWong, Carlos King Ho-
dc.contributor.authorYiu, Kai Hang-
dc.contributor.authorTse, Hung Fat-
dc.contributor.authorLau, Chak Sing-
dc.contributor.authorWong, Ian Chi Kei-
dc.contributor.authorChan, Esther Wai Yin-
dc.date.accessioned2024-03-11T10:21:10Z-
dc.date.available2024-03-11T10:21:10Z-
dc.date.issued2023-08-22-
dc.identifier.citationCell Reports Medicine, 2023, v. 4, n. 10-
dc.identifier.issn2666-3791-
dc.identifier.urihttp://hdl.handle.net/10722/337474-
dc.description.abstract<p> <span>It is unknown if vaccination affects the risk of post-COVID-19 cardiovascular diseases (CVDs). Therefore, this retrospective cohort study examines the short-term and long-term risks of post-infection CVD among COVID-19 patients with different vaccination status utilizing data from electronic health databases in Hong Kong. Cox proportional hazards regression adjusted with inverse probability of treatment weighting is used to evaluate the risks of incident CVD (coronary heart disease, stroke, heart failure) and all-cause mortality in COVID-19 patients. Compared with unvaccinated patients, vaccinated patients have a lower risk of CVD and all-cause mortality, and the lowest risk is observed in those who completed three doses of vaccine. Similar patterns in the subgroups of different vaccine platforms, age, gender, Charlson comorbidity index, and disease severity are observed. These findings highlight a positive dose-response relationship between overall CVD risk reduction and the number of vaccine doses received.</span> <br></p>-
dc.languageeng-
dc.publisherCell Press-
dc.relation.ispartofCell Reports Medicine-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectinactivated vaccine-
dc.subjectincident CVD-
dc.subjectlong COVID-
dc.subjectomicron-
dc.subjectpost-COVID CVD-
dc.subjectSARS-CoV-2-
dc.titleAssociation between BNT162b2 and CoronaVac vaccination and risk of CVD and mortality after COVID-19 infection: A population-based cohort study-
dc.typeArticle-
dc.identifier.doi10.1016/j.xcrm.2023.101195-
dc.identifier.scopuseid_2-s2.0-85173150384-
dc.identifier.volume4-
dc.identifier.issue10-
dc.identifier.eissn2666-3791-
dc.identifier.isiWOS:001101699600001-
dc.identifier.issnl2666-3791-

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