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- Publisher Website: 10.5005/jp-journals-10024-1667
- Scopus: eid_2-s2.0-85016649799
- PMID: 26057924
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Article: Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children
Title | Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children |
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Authors | |
Keywords | Dental caries Oxidative stress Saliva |
Issue Date | 2015 |
Citation | Journal of Contemporary Dental Practice, 2015, v. 16, n. 3, p. 234-237 How to Cite? |
Abstract | Background: Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism. Antioxidant capacity of saliva can constitute a first line of defense against chronic degenerative diseases including dental caries. Till date, no study is presented with salivary antioxidant capacity of younger children affected with severe early childhood caries with its salivary pH correlation. Hence, this study was carried out to compare, evaluate and correlate the salivary total antioxidant capacity (TAC) and salivary pH of children with caries-free and severe early childhood caries. Materials and methods: Fifty children from ages 3 to 5 years divided into two study groups had undergone screening. Group I (n = 25) with severe early childhood caries (S-ECC) and group II (n = 25) who were caries free. Unstimulated whole saliva of subjects were in the collection during the study by draining method. Salivary pH determination of saliva samples was done using pH indicator paper strips. The TAC was done using an antioxidant assay with the help of a spectrophotometer at wavelength 532 nm. The means of salivary pH and TAC were subjected to analysis using unpaired student ‘t’ test and correlation was determined using Pearsons correlation coefficient analysis. Results: Mean salivary pH was higher in group II (7.46 ± 0.37). Mean TAC was greater in group I (1.82 ± 0.19). A statistically significant negative correlation as seen between TAC and salivary pH in S-ECC patients. Conclusion: The study concludes that salivary TAC increases in patients with S-ECC are by that showing a high indirect relationship with salivary pH. |
Persistent Identifier | http://hdl.handle.net/10722/336174 |
DC Field | Value | Language |
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dc.contributor.author | Muchandi, Sneha | - |
dc.contributor.author | Walimbe, Hrishikesh | - |
dc.contributor.author | Bijle, Mohammed Nadeem Ahmed | - |
dc.contributor.author | Nankar, Meenakshi | - |
dc.contributor.author | Chaturvedi, Srishti | - |
dc.contributor.author | Karekar, Priyanka | - |
dc.date.accessioned | 2024-01-15T08:24:10Z | - |
dc.date.available | 2024-01-15T08:24:10Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Journal of Contemporary Dental Practice, 2015, v. 16, n. 3, p. 234-237 | - |
dc.identifier.uri | http://hdl.handle.net/10722/336174 | - |
dc.description.abstract | Background: Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism. Antioxidant capacity of saliva can constitute a first line of defense against chronic degenerative diseases including dental caries. Till date, no study is presented with salivary antioxidant capacity of younger children affected with severe early childhood caries with its salivary pH correlation. Hence, this study was carried out to compare, evaluate and correlate the salivary total antioxidant capacity (TAC) and salivary pH of children with caries-free and severe early childhood caries. Materials and methods: Fifty children from ages 3 to 5 years divided into two study groups had undergone screening. Group I (n = 25) with severe early childhood caries (S-ECC) and group II (n = 25) who were caries free. Unstimulated whole saliva of subjects were in the collection during the study by draining method. Salivary pH determination of saliva samples was done using pH indicator paper strips. The TAC was done using an antioxidant assay with the help of a spectrophotometer at wavelength 532 nm. The means of salivary pH and TAC were subjected to analysis using unpaired student ‘t’ test and correlation was determined using Pearsons correlation coefficient analysis. Results: Mean salivary pH was higher in group II (7.46 ± 0.37). Mean TAC was greater in group I (1.82 ± 0.19). A statistically significant negative correlation as seen between TAC and salivary pH in S-ECC patients. Conclusion: The study concludes that salivary TAC increases in patients with S-ECC are by that showing a high indirect relationship with salivary pH. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Contemporary Dental Practice | - |
dc.subject | Dental caries | - |
dc.subject | Oxidative stress | - |
dc.subject | Saliva | - |
dc.title | Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.5005/jp-journals-10024-1667 | - |
dc.identifier.pmid | 26057924 | - |
dc.identifier.scopus | eid_2-s2.0-85016649799 | - |
dc.identifier.volume | 16 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 234 | - |
dc.identifier.epage | 237 | - |
dc.identifier.eissn | 1526-3711 | - |