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Article: Detection of miRNA as non-invasive biomarkers of colorectal cancer

TitleDetection of miRNA as non-invasive biomarkers of colorectal cancer
Authors
KeywordsBiomarker
Circulatory
Colorectal cancer
Diagnostic
Fecal
miRNA
Issue Date2015
Citation
International Journal of Molecular Sciences, 2015, v. 16, n. 2, p. 2810-2823 How to Cite?
AbstractColorectal Cancer (CRC) is one of the deadliest cancers—ranking as the fourth most common cause of cancer-related deaths in the world. It is such a deadly disease because it is largely asymptomatic until the latter stages—oftentimes when the cancer has metastasized. Thus, a huge emphasis of cancer treatment is placed on early detection. Currently, there is a lack of a noninvasive, reliable, and cost-effective screening method for CRC. In recent years, microRNA (miRNA) diagnostic markers have been suggested as a viable new screening method for CRC. miRNAs play an important role in carcinogenesis, and has been observed to be dysregulated in many cancers including CRC. This review examines the diagnostic potential of circulatory and fecal miRNA markers in relation to CRC, as well as current techniques to detect them.
Persistent Identifierhttp://hdl.handle.net/10722/336132
ISSN
2023 Impact Factor: 4.9
2023 SCImago Journal Rankings: 1.179
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorRen, Albert-
dc.contributor.authorDong, Yujuan-
dc.contributor.authorTsoi, Ho-
dc.contributor.authorYu, Jun-
dc.date.accessioned2024-01-15T08:23:45Z-
dc.date.available2024-01-15T08:23:45Z-
dc.date.issued2015-
dc.identifier.citationInternational Journal of Molecular Sciences, 2015, v. 16, n. 2, p. 2810-2823-
dc.identifier.issn1661-6596-
dc.identifier.urihttp://hdl.handle.net/10722/336132-
dc.description.abstractColorectal Cancer (CRC) is one of the deadliest cancers—ranking as the fourth most common cause of cancer-related deaths in the world. It is such a deadly disease because it is largely asymptomatic until the latter stages—oftentimes when the cancer has metastasized. Thus, a huge emphasis of cancer treatment is placed on early detection. Currently, there is a lack of a noninvasive, reliable, and cost-effective screening method for CRC. In recent years, microRNA (miRNA) diagnostic markers have been suggested as a viable new screening method for CRC. miRNAs play an important role in carcinogenesis, and has been observed to be dysregulated in many cancers including CRC. This review examines the diagnostic potential of circulatory and fecal miRNA markers in relation to CRC, as well as current techniques to detect them.-
dc.languageeng-
dc.relation.ispartofInternational Journal of Molecular Sciences-
dc.subjectBiomarker-
dc.subjectCirculatory-
dc.subjectColorectal cancer-
dc.subjectDiagnostic-
dc.subjectFecal-
dc.subjectmiRNA-
dc.titleDetection of miRNA as non-invasive biomarkers of colorectal cancer-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3390/ijms16022810-
dc.identifier.pmid25633103-
dc.identifier.scopuseid_2-s2.0-84921898902-
dc.identifier.volume16-
dc.identifier.issue2-
dc.identifier.spage2810-
dc.identifier.epage2823-
dc.identifier.eissn1422-0067-
dc.identifier.isiWOS:000350333600031-

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