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Article: Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes

TitleNoninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes
Authors
Zavaleta, C.De La Zerda, A.Liu, Z.Keren, S.Cheng, Z.Schipper, M.Chen, X.Dai, H.Gambhir, S. S.
Issue Date2008
Citation
Nano Letters, 2008, v. 8, n. 9, p. 2800-2805 How to Cite?
DOI: http://dx.doi.org/10.1021/nl801362a
AbstractAn optimized noninvasive Raman microscope was used to evaluate tumor targeting and localization of single walled carbon nanotubes (SWNTs) in mice. Raman images were acquired in two groups of tumor-bearing mice. The control group received plain-SWNTs, whereas the experimental group received tumor targeting RGD-SWNTs intravenously. Raman imaging commenced over the next 72 h and revealed increased accumulation of RGD-SWNTs in tumor (p < 0.05) as opposed to plain-SWNTs. These results support the development of a new preclinical Raman imager. © 2008 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/334185
ISSN
1530-6984
2023 Impact Factor: 9.6
2023 SCImago Journal Rankings: 3.411
ISI Accession Number ID
WOS:000259140200034

 

DC FieldValueLanguage
dc.contributor.authorZavaleta, C.-
dc.contributor.authorDe La Zerda, A.-
dc.contributor.authorLiu, Z.-
dc.contributor.authorKeren, S.-
dc.contributor.authorCheng, Z.-
dc.contributor.authorSchipper, M.-
dc.contributor.authorChen, X.-
dc.contributor.authorDai, H.-
dc.contributor.authorGambhir, S. S.-
dc.date.accessioned2023-10-20T06:46:20Z-
dc.date.available2023-10-20T06:46:20Z-
dc.date.issued2008-
dc.identifier.citationNano Letters, 2008, v. 8, n. 9, p. 2800-2805-
dc.identifier.issn1530-6984-
dc.identifier.urihttp://hdl.handle.net/10722/334185-
dc.description.abstractAn optimized noninvasive Raman microscope was used to evaluate tumor targeting and localization of single walled carbon nanotubes (SWNTs) in mice. Raman images were acquired in two groups of tumor-bearing mice. The control group received plain-SWNTs, whereas the experimental group received tumor targeting RGD-SWNTs intravenously. Raman imaging commenced over the next 72 h and revealed increased accumulation of RGD-SWNTs in tumor (p < 0.05) as opposed to plain-SWNTs. These results support the development of a new preclinical Raman imager. © 2008 American Chemical Society.-
dc.languageeng-
dc.relation.ispartofNano Letters-
dc.titleNoninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/nl801362a-
dc.identifier.pmid18683988-
dc.identifier.scopuseid_2-s2.0-54549116271-
dc.identifier.volume8-
dc.identifier.issue9-
dc.identifier.spage2800-
dc.identifier.epage2805-
dc.identifier.isiWOS:000259140200034-

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