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- Publisher Website: 10.1021/acs.orglett.5b00740
- Scopus: eid_2-s2.0-84928888483
- PMID: 25894019
- WOS: WOS:000354004400028
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Article: Oxime Ligation on the Surface of Mesoporous Silica Nanoparticles
Title | Oxime Ligation on the Surface of Mesoporous Silica Nanoparticles |
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Authors | |
Issue Date | 2015 |
Citation | Organic Letters, 2015, v. 17, n. 9, p. 2146-2149 How to Cite? |
Abstract | (Chemical Equation Presented). A versatile surface-functionalization strategy applicable to mesoporous silica nanoparticles, which could potentially serve as drug delivery vehicles, is described that makes use of alkoxyamine tethers on the surface of the nanoparticles. A wide variety of carbonyl compounds can be attached readily to these tethers under the mild conditions of oxime ether formation, simply by incubating the chemically modified mesoporous silica nanoparticles with aldehydes or ketones in water. |
Persistent Identifier | http://hdl.handle.net/10722/333117 |
ISSN | 2023 Impact Factor: 4.9 2023 SCImago Journal Rankings: 1.245 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ferris, Daniel P. | - |
dc.contributor.author | McGonigal, Paul R. | - |
dc.contributor.author | Witus, Leah S. | - |
dc.contributor.author | Kawaji, Takatoshi | - |
dc.contributor.author | Algaradah, Mohammed M. | - |
dc.contributor.author | Alnajadah, Ahmed R. | - |
dc.contributor.author | Nassar, Majed S. | - |
dc.contributor.author | Stoddart, J. Fraser | - |
dc.date.accessioned | 2023-10-06T05:16:52Z | - |
dc.date.available | 2023-10-06T05:16:52Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Organic Letters, 2015, v. 17, n. 9, p. 2146-2149 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | http://hdl.handle.net/10722/333117 | - |
dc.description.abstract | (Chemical Equation Presented). A versatile surface-functionalization strategy applicable to mesoporous silica nanoparticles, which could potentially serve as drug delivery vehicles, is described that makes use of alkoxyamine tethers on the surface of the nanoparticles. A wide variety of carbonyl compounds can be attached readily to these tethers under the mild conditions of oxime ether formation, simply by incubating the chemically modified mesoporous silica nanoparticles with aldehydes or ketones in water. | - |
dc.language | eng | - |
dc.relation.ispartof | Organic Letters | - |
dc.title | Oxime Ligation on the Surface of Mesoporous Silica Nanoparticles | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1021/acs.orglett.5b00740 | - |
dc.identifier.pmid | 25894019 | - |
dc.identifier.scopus | eid_2-s2.0-84928888483 | - |
dc.identifier.volume | 17 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 2146 | - |
dc.identifier.epage | 2149 | - |
dc.identifier.eissn | 1523-7052 | - |
dc.identifier.isi | WOS:000354004400028 | - |