File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Linear artificial molecular muscles

TitleLinear artificial molecular muscles
Authors
Issue Date2005
Citation
Journal of the American Chemical Society, 2005, v. 127, n. 27, p. 9745-9759 How to Cite?
AbstractTwo switchable, palindromically constituted bistable [3]rotaxanes have been designed and synthesized with a pair of mechanically mobile rings encircling a single dumbbell. These designs are reminiscent of a "molecular muscle" for the purposes of amplifying and harnessing molecular mechanical motions. The location of the two cyclobis(paraquat-p-phenylene) (CBPQT4+) rings can be controlled to be on either tetrathiafulvalene (TTF) or naphthalene (NP) stations, either chemically (1H NMR spectroscopy) or electrochemically (cyclic voltammetry), such that switching of inter-ring distances from 4.2 to 1.4 nm mimics the contraction and extension of skeletal muscle, albeit on a shorter length scale. Fast scan-rate cyclic voltammetry at low temperatures reveals stepwise oxidations and movements of one-half of the [3]rotaxane and then of the other, a process that appears to be concerted at room temperature. The active form of the bistable [3]rotaxane bears disulfide tethers attached covalently to both of the CBPQT4+ ring components for the purpose of its self-assembly onto a gold surface. An array of flexible microcantilever beams, each coated on one side with a monolayer of 6 billion of the active bistable [3]rotaxane molecules, undergoes controllable and reversible bending up and down when it is exposed to the synchronous addition of aqueous chemical oxidants and reductants. The beam bending is correlated with flexing of the surface-bound molecular muscles, whereas a monolayer of the dumbbell alone is inactive under the same conditions. This observation supports the hypothesis that the cumulative nanoscale movements within surface-bound "molecular muscles" can be harnessed to perform larger-scale mechanical work. © 2005 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/332610
ISSN
2023 Impact Factor: 14.4
2023 SCImago Journal Rankings: 5.489
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLiu, Yi-
dc.contributor.authorFlood, Amar H.-
dc.contributor.authorBonvallet, Paul A.-
dc.contributor.authorVignon, Scott A.-
dc.contributor.authorNorthrop, Brian H.-
dc.contributor.authorTseng, Hsian Rong-
dc.contributor.authorJeppesen, Jan O.-
dc.contributor.authorHuang, Tony J.-
dc.contributor.authorBrough, Branden-
dc.contributor.authorBaller, Marko-
dc.contributor.authorMagonov, Sergei-
dc.contributor.authorSolares, Santiago D.-
dc.contributor.authorGoddard, William A.-
dc.contributor.authorHo, Chih Ming-
dc.contributor.authorFraser Stoddart, J.-
dc.date.accessioned2023-10-06T05:12:51Z-
dc.date.available2023-10-06T05:12:51Z-
dc.date.issued2005-
dc.identifier.citationJournal of the American Chemical Society, 2005, v. 127, n. 27, p. 9745-9759-
dc.identifier.issn0002-7863-
dc.identifier.urihttp://hdl.handle.net/10722/332610-
dc.description.abstractTwo switchable, palindromically constituted bistable [3]rotaxanes have been designed and synthesized with a pair of mechanically mobile rings encircling a single dumbbell. These designs are reminiscent of a "molecular muscle" for the purposes of amplifying and harnessing molecular mechanical motions. The location of the two cyclobis(paraquat-p-phenylene) (CBPQT4+) rings can be controlled to be on either tetrathiafulvalene (TTF) or naphthalene (NP) stations, either chemically (1H NMR spectroscopy) or electrochemically (cyclic voltammetry), such that switching of inter-ring distances from 4.2 to 1.4 nm mimics the contraction and extension of skeletal muscle, albeit on a shorter length scale. Fast scan-rate cyclic voltammetry at low temperatures reveals stepwise oxidations and movements of one-half of the [3]rotaxane and then of the other, a process that appears to be concerted at room temperature. The active form of the bistable [3]rotaxane bears disulfide tethers attached covalently to both of the CBPQT4+ ring components for the purpose of its self-assembly onto a gold surface. An array of flexible microcantilever beams, each coated on one side with a monolayer of 6 billion of the active bistable [3]rotaxane molecules, undergoes controllable and reversible bending up and down when it is exposed to the synchronous addition of aqueous chemical oxidants and reductants. The beam bending is correlated with flexing of the surface-bound molecular muscles, whereas a monolayer of the dumbbell alone is inactive under the same conditions. This observation supports the hypothesis that the cumulative nanoscale movements within surface-bound "molecular muscles" can be harnessed to perform larger-scale mechanical work. © 2005 American Chemical Society.-
dc.languageeng-
dc.relation.ispartofJournal of the American Chemical Society-
dc.titleLinear artificial molecular muscles-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/ja051088p-
dc.identifier.pmid15998079-
dc.identifier.scopuseid_2-s2.0-22144436256-
dc.identifier.volume127-
dc.identifier.issue27-
dc.identifier.spage9745-
dc.identifier.epage9759-
dc.identifier.isiWOS:000230434200030-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats