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Article: Optimal resource allocation in HIV self-testing secondary distribution among Chinese MSM: Data-driven integer programming models
Title | Optimal resource allocation in HIV self-testing secondary distribution among Chinese MSM: Data-driven integer programming models |
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Authors | |
Keywords | greedy algorithm HIV self-testing integer programming mathematical optimization secondary distribution |
Issue Date | 2022 |
Citation | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2022, v. 380, n. 2214, article no. 20210128 How to Cite? |
Abstract | Human immunodeficiency virus self-testing (HIVST) is an innovative and effective strategy important to the expansion of HIV testing coverage. Several innovative implementations of HIVST have been developed and piloted among some HIV high-risk populations like men who have sex with men (MSM) to meet the global testing target. One innovative strategy is the secondary distribution of HIVST, in which individuals (defined as indexes) were given multiple testing kits for both self-use (i.e.self-testing) and distribution to other people in their MSM social network (defined as alters). Studies about secondary HIVST distribution have mainly concentrated on developing new intervention approaches to further increase the effectiveness of this relatively new strategy from the perspective of traditional public health discipline. There are many points of HIVST secondary distribution in which mathematical modelling can play an important role. In this study, we considered secondary HIVST kits distribution in a resource-constrained situation and proposed two data-driven integer linear programming models to maximize the overall economic benefits of secondary HIVST kits distribution based on our present implementation data from Chinese MSM. The objective function took expansion of normal alters and detection of positive and newly-tested 'alters' into account. Based on solutions from solvers, we developed greedy algorithms to find final solutions for our linear programming models. Results showed that our proposed data-driven approach could improve the total health economic benefit of HIVST secondary distribution. This article is part of the theme issue 'Data science approaches to infectious disease surveillance'. |
Persistent Identifier | http://hdl.handle.net/10722/330461 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 0.870 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Jing, Fengshi | - |
dc.contributor.author | Zhang, Qingpeng | - |
dc.contributor.author | Ong, Jason J. | - |
dc.contributor.author | Xie, Yewei | - |
dc.contributor.author | Ni, Yuxin | - |
dc.contributor.author | Cheng, Mengyuan | - |
dc.contributor.author | Huang, Shanzi | - |
dc.contributor.author | Zhou, Yi | - |
dc.contributor.author | Tang, Weiming | - |
dc.date.accessioned | 2023-09-05T12:10:52Z | - |
dc.date.available | 2023-09-05T12:10:52Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2022, v. 380, n. 2214, article no. 20210128 | - |
dc.identifier.issn | 1364-503X | - |
dc.identifier.uri | http://hdl.handle.net/10722/330461 | - |
dc.description.abstract | Human immunodeficiency virus self-testing (HIVST) is an innovative and effective strategy important to the expansion of HIV testing coverage. Several innovative implementations of HIVST have been developed and piloted among some HIV high-risk populations like men who have sex with men (MSM) to meet the global testing target. One innovative strategy is the secondary distribution of HIVST, in which individuals (defined as indexes) were given multiple testing kits for both self-use (i.e.self-testing) and distribution to other people in their MSM social network (defined as alters). Studies about secondary HIVST distribution have mainly concentrated on developing new intervention approaches to further increase the effectiveness of this relatively new strategy from the perspective of traditional public health discipline. There are many points of HIVST secondary distribution in which mathematical modelling can play an important role. In this study, we considered secondary HIVST kits distribution in a resource-constrained situation and proposed two data-driven integer linear programming models to maximize the overall economic benefits of secondary HIVST kits distribution based on our present implementation data from Chinese MSM. The objective function took expansion of normal alters and detection of positive and newly-tested 'alters' into account. Based on solutions from solvers, we developed greedy algorithms to find final solutions for our linear programming models. Results showed that our proposed data-driven approach could improve the total health economic benefit of HIVST secondary distribution. This article is part of the theme issue 'Data science approaches to infectious disease surveillance'. | - |
dc.language | eng | - |
dc.relation.ispartof | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences | - |
dc.subject | greedy algorithm | - |
dc.subject | HIV self-testing | - |
dc.subject | integer programming | - |
dc.subject | mathematical optimization | - |
dc.subject | secondary distribution | - |
dc.title | Optimal resource allocation in HIV self-testing secondary distribution among Chinese MSM: Data-driven integer programming models | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1098/rsta.2021.0128 | - |
dc.identifier.scopus | eid_2-s2.0-85122330197 | - |
dc.identifier.volume | 380 | - |
dc.identifier.issue | 2214 | - |
dc.identifier.spage | article no. 20210128 | - |
dc.identifier.epage | article no. 20210128 | - |
dc.identifier.isi | WOS:000720844400007 | - |