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- Publisher Website: 10.1039/c4cs00300d
- Scopus: eid_2-s2.0-84930840257
- PMID: 25519856
- WOS: WOS:000353658000008
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Article: Two-dimensional graphene analogues for biomedical applications
Title | Two-dimensional graphene analogues for biomedical applications |
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Authors | |
Issue Date | 2015 |
Citation | Chemical Society Reviews, 2015, v. 44, n. 9, p. 2681-2701 How to Cite? |
Abstract | The increasing demand of clinical biomedicine and fast development of nanobiotechnology has substantially promoted the generation of a variety of organic/inorganic nanosystems for biomedical applications. Biocompatible two-dimensional (2D) graphene analogues (e.g., nanosheets of transition metal dichalcogenides, transition metal oxides, g-C3N4, Bi2Se3, BN, etc.), which are referred to as 2D-GAs, have emerged as a new unique family of nanomaterials that show unprecedented advantages and superior performances in biomedicine due to their unique compositional, structural and physicochemical features. In this review, we summarize the state-of-the-art progress of this dynamically developed material family with a particular focus on biomedical applications. After the introduction, the second section of the article summarizes a range of synthetic methods for new types of 2D-GAs as well as their surface functionalization. The subsequent section provides a snapshot on the use of these biocompatible 2D-GAs for a broad spectrum of biomedical applications, including therapeutic (photothermal/photodynamic therapy, chemotherapy and synergistic therapy), diagnostic (fluorescent/magnetic resonance/computed tomography/photoacoustic imaging) and theranostic (concurrent diagnostic imaging and therapy) applications, especially on oncology. In addition, we briefly present the biosensing applications of these 2D-GAs for the detection of biomacromolecules and their in vitro/in vivo biosafety evaluations. The last section summarizes some critical unresolved issues, possible challenges/obstacles and also proposes future perspectives related to the rational design and construction of 2D-GAs for biomedical engineering, which are believed to promote their clinical translations for benefiting the personalized medicine and human health. |
Persistent Identifier | http://hdl.handle.net/10722/329361 |
ISSN | 2023 Impact Factor: 40.4 2023 SCImago Journal Rankings: 12.511 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chen, Yu | - |
dc.contributor.author | Tan, Chaoliang | - |
dc.contributor.author | Zhang, Hua | - |
dc.contributor.author | Wang, Lianzhou | - |
dc.date.accessioned | 2023-08-09T03:32:14Z | - |
dc.date.available | 2023-08-09T03:32:14Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Chemical Society Reviews, 2015, v. 44, n. 9, p. 2681-2701 | - |
dc.identifier.issn | 0306-0012 | - |
dc.identifier.uri | http://hdl.handle.net/10722/329361 | - |
dc.description.abstract | The increasing demand of clinical biomedicine and fast development of nanobiotechnology has substantially promoted the generation of a variety of organic/inorganic nanosystems for biomedical applications. Biocompatible two-dimensional (2D) graphene analogues (e.g., nanosheets of transition metal dichalcogenides, transition metal oxides, g-C3N4, Bi2Se3, BN, etc.), which are referred to as 2D-GAs, have emerged as a new unique family of nanomaterials that show unprecedented advantages and superior performances in biomedicine due to their unique compositional, structural and physicochemical features. In this review, we summarize the state-of-the-art progress of this dynamically developed material family with a particular focus on biomedical applications. After the introduction, the second section of the article summarizes a range of synthetic methods for new types of 2D-GAs as well as their surface functionalization. The subsequent section provides a snapshot on the use of these biocompatible 2D-GAs for a broad spectrum of biomedical applications, including therapeutic (photothermal/photodynamic therapy, chemotherapy and synergistic therapy), diagnostic (fluorescent/magnetic resonance/computed tomography/photoacoustic imaging) and theranostic (concurrent diagnostic imaging and therapy) applications, especially on oncology. In addition, we briefly present the biosensing applications of these 2D-GAs for the detection of biomacromolecules and their in vitro/in vivo biosafety evaluations. The last section summarizes some critical unresolved issues, possible challenges/obstacles and also proposes future perspectives related to the rational design and construction of 2D-GAs for biomedical engineering, which are believed to promote their clinical translations for benefiting the personalized medicine and human health. | - |
dc.language | eng | - |
dc.relation.ispartof | Chemical Society Reviews | - |
dc.title | Two-dimensional graphene analogues for biomedical applications | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1039/c4cs00300d | - |
dc.identifier.pmid | 25519856 | - |
dc.identifier.scopus | eid_2-s2.0-84930840257 | - |
dc.identifier.volume | 44 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 2681 | - |
dc.identifier.epage | 2701 | - |
dc.identifier.eissn | 1460-4744 | - |
dc.identifier.isi | WOS:000353658000008 | - |