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Article: The modulation of stem cell behaviors by functionalized nanoceramic coatings on Ti-based implants

TitleThe modulation of stem cell behaviors by functionalized nanoceramic coatings on Ti-based implants
Authors
KeywordsImplants
Modulation
Nanoceramic coating
Stem cell
Ti
Issue Date13-Sep-2016
PublisherElsevier
Citation
Bioactive Materials, 2016, v. 1, n. 1, p. 65-76 How to Cite?
AbstractNanoceramic coating on the surface of Ti-based metallic implants is a clinical potential option in orthopedic surgery. Stem cells have been found to have osteogenic capabilities. It is necessary to study the influences of functionalized nanoceramic coatings on the differentiation and proliferation of stem cells in vitro or in vivo. In this paper, we summarized the recent advance on the modulation of stem cells behaviors through controlling the properties of nanoceramic coatings, including surface chemistry, surface roughness and microporosity. In addition, mechanotransduction pathways have also been discussed to reveal the interaction mechanisms between the stem cells and ceramic coatings on Ti-based metals. In the final part, the osteoinduction and osteoconduction of ceramic coating have been also presented when it was used as carrier of BMPs in new bone formation.
Persistent Identifierhttp://hdl.handle.net/10722/329201
ISSN
2023 Impact Factor: 18.0
2023 SCImago Journal Rankings: 3.466
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLiu, XM-
dc.contributor.authorLi, M-
dc.contributor.authorZhu, YZ-
dc.contributor.authorYeung, KWK-
dc.contributor.authorChu, PK-
dc.contributor.authorWu, SL-
dc.date.accessioned2023-08-05T07:56:03Z-
dc.date.available2023-08-05T07:56:03Z-
dc.date.issued2016-09-13-
dc.identifier.citationBioactive Materials, 2016, v. 1, n. 1, p. 65-76-
dc.identifier.issn2452-199X-
dc.identifier.urihttp://hdl.handle.net/10722/329201-
dc.description.abstractNanoceramic coating on the surface of Ti-based metallic implants is a clinical potential option in orthopedic surgery. Stem cells have been found to have osteogenic capabilities. It is necessary to study the influences of functionalized nanoceramic coatings on the differentiation and proliferation of stem cells in vitro or in vivo. In this paper, we summarized the recent advance on the modulation of stem cells behaviors through controlling the properties of nanoceramic coatings, including surface chemistry, surface roughness and microporosity. In addition, mechanotransduction pathways have also been discussed to reveal the interaction mechanisms between the stem cells and ceramic coatings on Ti-based metals. In the final part, the osteoinduction and osteoconduction of ceramic coating have been also presented when it was used as carrier of BMPs in new bone formation.-
dc.languageeng-
dc.publisherElsevier-
dc.relation.ispartofBioactive Materials-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectImplants-
dc.subjectModulation-
dc.subjectNanoceramic coating-
dc.subjectStem cell-
dc.subjectTi-
dc.titleThe modulation of stem cell behaviors by functionalized nanoceramic coatings on Ti-based implants-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1016/j.bioactmat.2016.09.001-
dc.identifier.scopuseid_2-s2.0-85007091100-
dc.identifier.volume1-
dc.identifier.issue1-
dc.identifier.spage65-
dc.identifier.epage76-
dc.identifier.eissn2452-199X-
dc.identifier.isiWOS:000446877900007-
dc.identifier.issnl2452-199X-

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