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Article: Tumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment

TitleTumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment
Authors
KeywordsExosome
Extracellular vesicles
Hepatocellular carcinoma
Tumor formation and progression
Issue Date2022
Citation
Journal of Clinical and Translational Hepatology, 2022, v. 10, n. 3, p. 496-508 How to Cite?
AbstractHepatocellular carcinoma (HCC) has become a challenging disease worldwide. There are still limitations in the diagnosis and treatment of HCC, and its high metastatic capac-ity and high recurrence rate are the main reasons for its poor prognosis. The ability of extracellular vesicles (EVs) to transfer functionally-active substances and their wide-spread presence in almost all body fluids suggest their un-precedented potential in the study of various cancers. The unique physicochemical properties of EVs determine their potential as antitumor vaccines and drug carriers. In the last decade, the study of EVs in HCC has evolved from a single hot topic to a system with considerable scale. This paper summarizes the role of EVs, especially exosomes, in the occurrence, metastasis and tumor immunity of HCC, re-views their applications in tumor diagnosis, prognosis and treatment, describes the pros and cons of these studies, and looks forward towards the future research directions of EVs in HCC.
Persistent Identifierhttp://hdl.handle.net/10722/325571
ISSN
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.988
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWang, Hang-
dc.contributor.authorYu, Liang-
dc.contributor.authorHuang, Peng-
dc.contributor.authorZhou, Yongxu-
dc.contributor.authorZheng, Wangyang-
dc.contributor.authorMeng, Nanfeng-
dc.contributor.authorHe, Risheng-
dc.contributor.authorXu, Yi-
dc.contributor.authorKeong, Tey Sze-
dc.contributor.authorCui, Yunfu-
dc.date.accessioned2023-02-27T07:34:23Z-
dc.date.available2023-02-27T07:34:23Z-
dc.date.issued2022-
dc.identifier.citationJournal of Clinical and Translational Hepatology, 2022, v. 10, n. 3, p. 496-508-
dc.identifier.issn2225-0719-
dc.identifier.urihttp://hdl.handle.net/10722/325571-
dc.description.abstractHepatocellular carcinoma (HCC) has become a challenging disease worldwide. There are still limitations in the diagnosis and treatment of HCC, and its high metastatic capac-ity and high recurrence rate are the main reasons for its poor prognosis. The ability of extracellular vesicles (EVs) to transfer functionally-active substances and their wide-spread presence in almost all body fluids suggest their un-precedented potential in the study of various cancers. The unique physicochemical properties of EVs determine their potential as antitumor vaccines and drug carriers. In the last decade, the study of EVs in HCC has evolved from a single hot topic to a system with considerable scale. This paper summarizes the role of EVs, especially exosomes, in the occurrence, metastasis and tumor immunity of HCC, re-views their applications in tumor diagnosis, prognosis and treatment, describes the pros and cons of these studies, and looks forward towards the future research directions of EVs in HCC.-
dc.languageeng-
dc.relation.ispartofJournal of Clinical and Translational Hepatology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectExosome-
dc.subjectExtracellular vesicles-
dc.subjectHepatocellular carcinoma-
dc.subjectTumor formation and progression-
dc.titleTumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.14218/JCTH.2021.00425-
dc.identifier.pmid35836772-
dc.identifier.pmcidPMC9240252-
dc.identifier.scopuseid_2-s2.0-85134039820-
dc.identifier.volume10-
dc.identifier.issue3-
dc.identifier.spage496-
dc.identifier.epage508-
dc.identifier.eissn2310-8819-
dc.identifier.isiWOS:000792956000001-

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