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- Scopus: eid_2-s2.0-1242351877
- PMID: 14733774
- WOS: WOS:000189012400012
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Article: Vagus nerve stimulation for refractory epilepsy: Long term efficacy and side-effects
Title | Vagus nerve stimulation for refractory epilepsy: Long term efficacy and side-effects |
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Authors | |
Keywords | Chinese population Epilepsy surgery Refractory epilepsy Vagus nerve stimulation |
Issue Date | 2004 |
Citation | Chinese Medical Journal, 2004, v. 117, n. 1, p. 58-61 How to Cite? |
Abstract | Background. In general vagus nerve stimulation (VNS) can serve as an adjunctive treatment for patients with refractory partial -onset seizures. And we evaluated the long-term efficacy and safety of VNS in a group of Chinese patients with refratory epilepsy. Methods. Of 127 patients with refractory epilepsy, 13 patients who were not eligible for surgical intervention were implanted with the Cyberonics VNS system. Seizure frequency, physical examination and side effects profile were recorded at follow-up visits for a minimum of 18 months. Results. Mean duration of treatment was 47.4 months, and the longest follow-up period was 71 months. Mean baseline seizure frequency was 26.6 seizures per month. The mean percentage reductions in convulsions were 33.2%, 47.1% and 40.0% at 6, 12 and 18 months, respectively. One patient became seizure free, and six (46%) had 50% or more reduction in seizure frequency. Response was poor (<20% reduction) in five patients (39%). Side effects were uncommon. Conclusions. The effectiveness of VNS was sustained and was well tolerated but benefited only a sub-group of patients with intractable convulsions. |
Persistent Identifier | http://hdl.handle.net/10722/325085 |
ISSN | 2023 Impact Factor: 7.5 2023 SCImago Journal Rankings: 0.997 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Hui, Andrew Che Fai | - |
dc.contributor.author | Lam, Joseph Man Kuen | - |
dc.contributor.author | Wong, Ka Shing | - |
dc.contributor.author | Kay, Richard | - |
dc.contributor.author | Poon, Wai Sing | - |
dc.date.accessioned | 2023-02-27T07:29:35Z | - |
dc.date.available | 2023-02-27T07:29:35Z | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Chinese Medical Journal, 2004, v. 117, n. 1, p. 58-61 | - |
dc.identifier.issn | 0366-6999 | - |
dc.identifier.uri | http://hdl.handle.net/10722/325085 | - |
dc.description.abstract | Background. In general vagus nerve stimulation (VNS) can serve as an adjunctive treatment for patients with refractory partial -onset seizures. And we evaluated the long-term efficacy and safety of VNS in a group of Chinese patients with refratory epilepsy. Methods. Of 127 patients with refractory epilepsy, 13 patients who were not eligible for surgical intervention were implanted with the Cyberonics VNS system. Seizure frequency, physical examination and side effects profile were recorded at follow-up visits for a minimum of 18 months. Results. Mean duration of treatment was 47.4 months, and the longest follow-up period was 71 months. Mean baseline seizure frequency was 26.6 seizures per month. The mean percentage reductions in convulsions were 33.2%, 47.1% and 40.0% at 6, 12 and 18 months, respectively. One patient became seizure free, and six (46%) had 50% or more reduction in seizure frequency. Response was poor (<20% reduction) in five patients (39%). Side effects were uncommon. Conclusions. The effectiveness of VNS was sustained and was well tolerated but benefited only a sub-group of patients with intractable convulsions. | - |
dc.language | eng | - |
dc.relation.ispartof | Chinese Medical Journal | - |
dc.subject | Chinese population | - |
dc.subject | Epilepsy surgery | - |
dc.subject | Refractory epilepsy | - |
dc.subject | Vagus nerve stimulation | - |
dc.title | Vagus nerve stimulation for refractory epilepsy: Long term efficacy and side-effects | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 14733774 | - |
dc.identifier.scopus | eid_2-s2.0-1242351877 | - |
dc.identifier.volume | 117 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 58 | - |
dc.identifier.epage | 61 | - |
dc.identifier.isi | WOS:000189012400012 | - |