File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1007/s12975-013-0284-z
- Scopus: eid_2-s2.0-84896403684
- PMID: 24323708
- WOS: WOS:000333050000014
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Early MoCA-Assessed Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage and Relationship to 1-Year Functional Outcome
Title | Early MoCA-Assessed Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage and Relationship to 1-Year Functional Outcome |
---|---|
Authors | |
Keywords | Cerebral aneurysm Cognition Montreal cognitive assessment Subarachnoid hemorrhage |
Issue Date | 2014 |
Citation | Translational Stroke Research, 2014, v. 5, n. 2, p. 286-291 How to Cite? |
Abstract | Recent clinical research into aneurysmal subarachnoid hemorrhage (aSAH) has confirmed the long-term effect of cognitive dysfunction on functional outcomes. We hypothesized that early cognitive impairment was a marker of permanent brain injury and hence predicted long-term functional outcome. Hong Kong Chinese patients with aneurysmal subarachnoid hemorrhage were evaluated prospectively by means of the Montreal Cognitive Assessment (MoCA) in the subacute phase (2-4 weeks after aSAH) and by neuropsychological evaluation of functional outcomes in the chronic phase (1 year after aSAH). This multi-center prospective observational study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193). One hundred and eight patients completed both the subacute and chronic phase assessments. Cognitive dysfunction in the subacute phase independently correlated with functional outcomes at 1 year, after adjusting for age, admission clinical condition, treatment modality, motor score, and mobility in the subacute phase, but the positive predictive values remained low. MoCA-assessed cognitive impairment in the subacute phase cannot accurately predict functional outcomes at 1 year. Future study should focus on understanding the relative importance of different components of early cognitive impairment. © 2013 Springer Science+Business Media New York. |
Persistent Identifier | http://hdl.handle.net/10722/324950 |
ISSN | 2023 Impact Factor: 3.8 2023 SCImago Journal Rankings: 1.595 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, George Kwok Chu | - |
dc.contributor.author | Lam, Sandy Wai | - |
dc.contributor.author | Wong, Adrian | - |
dc.contributor.author | Mok, Vincent | - |
dc.contributor.author | Siu, Deyond | - |
dc.contributor.author | Ngai, Karine | - |
dc.contributor.author | Poon, Wai Sang | - |
dc.date.accessioned | 2023-02-27T07:28:30Z | - |
dc.date.available | 2023-02-27T07:28:30Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Translational Stroke Research, 2014, v. 5, n. 2, p. 286-291 | - |
dc.identifier.issn | 1868-4483 | - |
dc.identifier.uri | http://hdl.handle.net/10722/324950 | - |
dc.description.abstract | Recent clinical research into aneurysmal subarachnoid hemorrhage (aSAH) has confirmed the long-term effect of cognitive dysfunction on functional outcomes. We hypothesized that early cognitive impairment was a marker of permanent brain injury and hence predicted long-term functional outcome. Hong Kong Chinese patients with aneurysmal subarachnoid hemorrhage were evaluated prospectively by means of the Montreal Cognitive Assessment (MoCA) in the subacute phase (2-4 weeks after aSAH) and by neuropsychological evaluation of functional outcomes in the chronic phase (1 year after aSAH). This multi-center prospective observational study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193). One hundred and eight patients completed both the subacute and chronic phase assessments. Cognitive dysfunction in the subacute phase independently correlated with functional outcomes at 1 year, after adjusting for age, admission clinical condition, treatment modality, motor score, and mobility in the subacute phase, but the positive predictive values remained low. MoCA-assessed cognitive impairment in the subacute phase cannot accurately predict functional outcomes at 1 year. Future study should focus on understanding the relative importance of different components of early cognitive impairment. © 2013 Springer Science+Business Media New York. | - |
dc.language | eng | - |
dc.relation.ispartof | Translational Stroke Research | - |
dc.subject | Cerebral aneurysm | - |
dc.subject | Cognition | - |
dc.subject | Montreal cognitive assessment | - |
dc.subject | Subarachnoid hemorrhage | - |
dc.title | Early MoCA-Assessed Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage and Relationship to 1-Year Functional Outcome | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/s12975-013-0284-z | - |
dc.identifier.pmid | 24323708 | - |
dc.identifier.scopus | eid_2-s2.0-84896403684 | - |
dc.identifier.volume | 5 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 286 | - |
dc.identifier.epage | 291 | - |
dc.identifier.eissn | 1868-601X | - |
dc.identifier.isi | WOS:000333050000014 | - |