File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1111/j.1469-7610.2006.01684.x
- Scopus: eid_2-s2.0-33750422608
- PMID: 17073983
- WOS: WOS:000241625200009
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Deficient orthographic and phonological representations in children with dyslexia revealed by brain activation patterns
Title | Deficient orthographic and phonological representations in children with dyslexia revealed by brain activation patterns |
---|---|
Authors | |
Keywords | Brain imaging Dyslexia Learning difficulties Magnetic resonance imaging Phonological processing Reading disorder |
Issue Date | 2006 |
Citation | Journal of Child Psychology and Psychiatry and Allied Disciplines, 2006, v. 47, n. 10, p. 1041-1050 How to Cite? |
Abstract | Background: The current study examined the neuro-cognitive network of visual word rhyming judgment in 14 children with dyslexia and 14 age-matched control children (8- to 14-year-olds) using functional magnetic resonance imaging (fMRI). Methods: In order to manipulate the difficulty of mapping orthography to phonology, we used conflicting and non-conflicting trials. The words in conflicting trials either had similar orthography but different phonology (e.g., pint-mint) or similar phonology but different orthography (e.g., jazz-has). The words in non-conflicting trials had similar orthography and phonology (e.g., gate-hate) or different orthography and phonology (e.g., press-list). Results: There were no differences in brain activation between the controls and children with dyslexia in the easier non-conflicting trials. However, the children with dyslexia showed less activation than the controls in left inferior frontal gyrus (BA 45/44/47/9), left inferior parietal lobule (BA 40), left inferior temporal gyrus/fusiform gyrus (BA 20/37) and left middle temporal gyrus (BA 21) for the more difficult conflicting trials. For the direct comparison of conflicting minus non-conflicting trials, controls showed greater activation than children with dyslexia in left inferior frontal gyrus (BA 9/45/46) and medial frontal gyrus (BA 8). Children with dyslexia did not show greater activation than controls for any comparison. Conclusions: Reduced activation in these regions suggests that children with dyslexia have deficient orthographic representations in ventral temporal cortex as well as deficits in mapping between orthographic and phonological representations in inferior parietal cortex. The greater activation for the controls in inferior frontal gyrus could reflect more effective top-down modulation of posterior representations. © 2006 The Authors Journal compilation © 2006 Association for Child and Adolescent Mental Health. |
Persistent Identifier | http://hdl.handle.net/10722/321312 |
ISSN | 2023 Impact Factor: 6.5 2023 SCImago Journal Rankings: 3.133 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cao, Fan | - |
dc.contributor.author | Bitan, Tali | - |
dc.contributor.author | Chou, Tai Li | - |
dc.contributor.author | Burman, Douglas D. | - |
dc.contributor.author | Booth, James R. | - |
dc.date.accessioned | 2022-11-03T02:18:04Z | - |
dc.date.available | 2022-11-03T02:18:04Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Journal of Child Psychology and Psychiatry and Allied Disciplines, 2006, v. 47, n. 10, p. 1041-1050 | - |
dc.identifier.issn | 0021-9630 | - |
dc.identifier.uri | http://hdl.handle.net/10722/321312 | - |
dc.description.abstract | Background: The current study examined the neuro-cognitive network of visual word rhyming judgment in 14 children with dyslexia and 14 age-matched control children (8- to 14-year-olds) using functional magnetic resonance imaging (fMRI). Methods: In order to manipulate the difficulty of mapping orthography to phonology, we used conflicting and non-conflicting trials. The words in conflicting trials either had similar orthography but different phonology (e.g., pint-mint) or similar phonology but different orthography (e.g., jazz-has). The words in non-conflicting trials had similar orthography and phonology (e.g., gate-hate) or different orthography and phonology (e.g., press-list). Results: There were no differences in brain activation between the controls and children with dyslexia in the easier non-conflicting trials. However, the children with dyslexia showed less activation than the controls in left inferior frontal gyrus (BA 45/44/47/9), left inferior parietal lobule (BA 40), left inferior temporal gyrus/fusiform gyrus (BA 20/37) and left middle temporal gyrus (BA 21) for the more difficult conflicting trials. For the direct comparison of conflicting minus non-conflicting trials, controls showed greater activation than children with dyslexia in left inferior frontal gyrus (BA 9/45/46) and medial frontal gyrus (BA 8). Children with dyslexia did not show greater activation than controls for any comparison. Conclusions: Reduced activation in these regions suggests that children with dyslexia have deficient orthographic representations in ventral temporal cortex as well as deficits in mapping between orthographic and phonological representations in inferior parietal cortex. The greater activation for the controls in inferior frontal gyrus could reflect more effective top-down modulation of posterior representations. © 2006 The Authors Journal compilation © 2006 Association for Child and Adolescent Mental Health. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Child Psychology and Psychiatry and Allied Disciplines | - |
dc.subject | Brain imaging | - |
dc.subject | Dyslexia | - |
dc.subject | Learning difficulties | - |
dc.subject | Magnetic resonance imaging | - |
dc.subject | Phonological processing | - |
dc.subject | Reading disorder | - |
dc.title | Deficient orthographic and phonological representations in children with dyslexia revealed by brain activation patterns | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/j.1469-7610.2006.01684.x | - |
dc.identifier.pmid | 17073983 | - |
dc.identifier.scopus | eid_2-s2.0-33750422608 | - |
dc.identifier.volume | 47 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1041 | - |
dc.identifier.epage | 1050 | - |
dc.identifier.eissn | 1469-7610 | - |
dc.identifier.isi | WOS:000241625200009 | - |