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Article: Biomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite

TitleBiomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite
Authors
KeywordsBiomimetic
Nanocomposites
Nanocrystals
Strontium hydroxyapatite
Type I collagen
Issue Date2020
Citation
Materials Letters, 2020, v. 274, article no. 127982 How to Cite?
AbstractStrontium-releasing bioactive materials have attracted considerable attention for patients with osteoporotic bone defects due to its ability to stimulate bone formation and decrease bone resorption. In the present study, type I collagen/strontium hydroxyapatite nanocomposite (cSrHA) was fabricated via a non-classical biomimetic mineralization pathway. Mineralized collagen fibrils with nanosized SrHA embedded in intrafibrillar interstices were obtained using poly(acrylic acid) as a biomimetic mineralizing director. The resultant nanocomposite was characterized by SEM, TEM, EDS, ATR-FTIR, XRD and TGA. cSrHA displayed morphologies, nanostructures and characteristics similar to those of natural hard tissue and calcium hydroxyapatite-mineralized collagen (cCaHA), indicating its potential value as a biofunctional material for bone engineering.
Persistent Identifierhttp://hdl.handle.net/10722/318827
ISSN
2023 Impact Factor: 2.7
2023 SCImago Journal Rankings: 0.602
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorQi, Yipin-
dc.contributor.authorMai, Sui-
dc.contributor.authorYe, Zhou-
dc.contributor.authorAparicio, Conrado-
dc.date.accessioned2022-10-11T12:24:39Z-
dc.date.available2022-10-11T12:24:39Z-
dc.date.issued2020-
dc.identifier.citationMaterials Letters, 2020, v. 274, article no. 127982-
dc.identifier.issn0167-577X-
dc.identifier.urihttp://hdl.handle.net/10722/318827-
dc.description.abstractStrontium-releasing bioactive materials have attracted considerable attention for patients with osteoporotic bone defects due to its ability to stimulate bone formation and decrease bone resorption. In the present study, type I collagen/strontium hydroxyapatite nanocomposite (cSrHA) was fabricated via a non-classical biomimetic mineralization pathway. Mineralized collagen fibrils with nanosized SrHA embedded in intrafibrillar interstices were obtained using poly(acrylic acid) as a biomimetic mineralizing director. The resultant nanocomposite was characterized by SEM, TEM, EDS, ATR-FTIR, XRD and TGA. cSrHA displayed morphologies, nanostructures and characteristics similar to those of natural hard tissue and calcium hydroxyapatite-mineralized collagen (cCaHA), indicating its potential value as a biofunctional material for bone engineering.-
dc.languageeng-
dc.relation.ispartofMaterials Letters-
dc.subjectBiomimetic-
dc.subjectNanocomposites-
dc.subjectNanocrystals-
dc.subjectStrontium hydroxyapatite-
dc.subjectType I collagen-
dc.titleBiomimetic fabrication and characterization of collagen/strontium hydroxyapatite nanocomposite-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.matlet.2020.127982-
dc.identifier.scopuseid_2-s2.0-85085236955-
dc.identifier.volume274-
dc.identifier.spagearticle no. 127982-
dc.identifier.epagearticle no. 127982-
dc.identifier.eissn1873-4979-
dc.identifier.isiWOS:000541705400004-

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