File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1080/13550280701329646
- Scopus: eid_2-s2.0-34447321575
- PMID: 17613719
- WOS: WOS:000247778900012
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis
Title | A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis |
---|---|
Authors | |
Keywords | Arbovirus DNA Encephalitis Mucosal Oral Prime-boost Sindbis virus Vaccination |
Issue Date | 2007 |
Citation | Journal of NeuroVirology, 2007, v. 13, n. 3, p. 284-289 How to Cite? |
Abstract | Arboviruses of the families Togaviridae and Flaviviridae are widely distributed and are important causative agents of viral encephalitis, a severe and often fatal disease. The only internationally available vaccine against these diseases is expensive and laborious to manufacture and difficult to administer. Therefore, new vaccines are required against these pathogens. This study investigates the use of a DNA-prime, orally delivered protein boost vaccination strategy against viral encephalitis. This vaccination strategy was immunogenic and provided partial protection against viral encephalitis in a murine model, demonstrating the possible applicability of this vaccination strategy for the management of endemic encephalitis. |
Persistent Identifier | http://hdl.handle.net/10722/311917 |
ISSN | 2023 Impact Factor: 2.3 2023 SCImago Journal Rankings: 0.653 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zanin, Mark P. | - |
dc.contributor.author | Webster, Diane E. | - |
dc.contributor.author | Wesselingh, Steven L. | - |
dc.date.accessioned | 2022-04-06T04:31:45Z | - |
dc.date.available | 2022-04-06T04:31:45Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Journal of NeuroVirology, 2007, v. 13, n. 3, p. 284-289 | - |
dc.identifier.issn | 1355-0284 | - |
dc.identifier.uri | http://hdl.handle.net/10722/311917 | - |
dc.description.abstract | Arboviruses of the families Togaviridae and Flaviviridae are widely distributed and are important causative agents of viral encephalitis, a severe and often fatal disease. The only internationally available vaccine against these diseases is expensive and laborious to manufacture and difficult to administer. Therefore, new vaccines are required against these pathogens. This study investigates the use of a DNA-prime, orally delivered protein boost vaccination strategy against viral encephalitis. This vaccination strategy was immunogenic and provided partial protection against viral encephalitis in a murine model, demonstrating the possible applicability of this vaccination strategy for the management of endemic encephalitis. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of NeuroVirology | - |
dc.subject | Arbovirus | - |
dc.subject | DNA | - |
dc.subject | Encephalitis | - |
dc.subject | Mucosal | - |
dc.subject | Oral | - |
dc.subject | Prime-boost | - |
dc.subject | Sindbis virus | - |
dc.subject | Vaccination | - |
dc.title | A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1080/13550280701329646 | - |
dc.identifier.pmid | 17613719 | - |
dc.identifier.scopus | eid_2-s2.0-34447321575 | - |
dc.identifier.volume | 13 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 284 | - |
dc.identifier.epage | 289 | - |
dc.identifier.isi | WOS:000247778900012 | - |