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Article: Effects of a group-based lifestyle medicine for depression: A pilot randomized controlled trial

TitleEffects of a group-based lifestyle medicine for depression: A pilot randomized controlled trial
Authors
Issue Date2021
PublisherPublic Library of Science. The Journal's web site is located at http://www.plosone.org/home.action
Citation
PLoS One, 2021, v. 16, p. article no. e0258059 How to Cite?
AbstractGiven the growing evidence that a range of lifestyle factors are involved in the etiology of depression, a ‘lifestyle medicine’ approach can be potentially safe and cost-effective to prevent or treat depression. To examine the effects and acceptability of a group-based, integrative lifestyle medicine intervention as a standalone treatment for managing depressive symptoms, a pilot randomized controlled trial (RCT) was conducted in a Chinese adult population in 2018. Participants (n = 31) with PHQ-9 score above the cut-off of ≥ 10, which was indicative of moderate to severe depression, were recruited from the general community in Hong Kong and randomly assigned to lifestyle medicine group (LM group) or care-as-usual group (CAU group) in a ratio of 1:1. Participants in the LM group received 2-hour group sessions once per week for six consecutive weeks, which covered diet, exercise, mindfulness, psychoeducation, and sleep management. Linear mixed-effects model analyses showed that the LM group had a significant reduction in PHQ-9 scores compared to the CAU group at immediate posttreatment and 12-week posttreatment follow-up (d = 0.69 and 0.73, respectively). Moreover, there were significantly greater improvements in anxiety, stress, and insomnia symptoms (measured by DASS-21 and ISI) at all time points in the LM group (d = 0.42–1.16). The results suggests that our 6-week group-based, integrative lifestyle intervention program is effective in lowering depressive, anxiety, stress, and insomnia symptoms in the Chinese population. Further studies in clinical populations with a larger sample size and longer follow-up are warranted.
Persistent Identifierhttp://hdl.handle.net/10722/310597
ISSN
2023 Impact Factor: 2.9
2023 SCImago Journal Rankings: 0.839
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorIp, AKY-
dc.contributor.authorHo, FYY-
dc.contributor.authorYeung, WF-
dc.contributor.authorChung, KF-
dc.contributor.authorNg, CH-
dc.contributor.authorOliver, G-
dc.contributor.authorSarris, J-
dc.date.accessioned2022-02-07T07:59:02Z-
dc.date.available2022-02-07T07:59:02Z-
dc.date.issued2021-
dc.identifier.citationPLoS One, 2021, v. 16, p. article no. e0258059-
dc.identifier.issn1932-6203-
dc.identifier.urihttp://hdl.handle.net/10722/310597-
dc.description.abstractGiven the growing evidence that a range of lifestyle factors are involved in the etiology of depression, a ‘lifestyle medicine’ approach can be potentially safe and cost-effective to prevent or treat depression. To examine the effects and acceptability of a group-based, integrative lifestyle medicine intervention as a standalone treatment for managing depressive symptoms, a pilot randomized controlled trial (RCT) was conducted in a Chinese adult population in 2018. Participants (n = 31) with PHQ-9 score above the cut-off of ≥ 10, which was indicative of moderate to severe depression, were recruited from the general community in Hong Kong and randomly assigned to lifestyle medicine group (LM group) or care-as-usual group (CAU group) in a ratio of 1:1. Participants in the LM group received 2-hour group sessions once per week for six consecutive weeks, which covered diet, exercise, mindfulness, psychoeducation, and sleep management. Linear mixed-effects model analyses showed that the LM group had a significant reduction in PHQ-9 scores compared to the CAU group at immediate posttreatment and 12-week posttreatment follow-up (d = 0.69 and 0.73, respectively). Moreover, there were significantly greater improvements in anxiety, stress, and insomnia symptoms (measured by DASS-21 and ISI) at all time points in the LM group (d = 0.42–1.16). The results suggests that our 6-week group-based, integrative lifestyle intervention program is effective in lowering depressive, anxiety, stress, and insomnia symptoms in the Chinese population. Further studies in clinical populations with a larger sample size and longer follow-up are warranted.-
dc.languageeng-
dc.publisherPublic Library of Science. The Journal's web site is located at http://www.plosone.org/home.action-
dc.relation.ispartofPLoS One-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleEffects of a group-based lifestyle medicine for depression: A pilot randomized controlled trial-
dc.typeArticle-
dc.identifier.emailChung, KF: kfchung@hku.hk-
dc.identifier.authorityChung, KF=rp00377-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1371/journal.pone.0258059-
dc.identifier.pmid34624047-
dc.identifier.pmcidPMC8500430-
dc.identifier.scopuseid_2-s2.0-85116937929-
dc.identifier.hkuros331667-
dc.identifier.volume16-
dc.identifier.spagearticle no. e0258059-
dc.identifier.epagearticle no. e0258059-
dc.identifier.isiWOS:000755691200014-
dc.publisher.placeUnited States-

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