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- Publisher Website: 10.1016/j.ijid.2020.10.102
- Scopus: eid_2-s2.0-85097743311
- PMID: 33160065
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Article: A child with acute myeloid leukemia complicated by calcaneal osteomyelitis due to Mycobacterium abscessus infection after induction chemotherapy successfully salvaged with bedaquiline and clofazimine
Title | A child with acute myeloid leukemia complicated by calcaneal osteomyelitis due to Mycobacterium abscessus infection after induction chemotherapy successfully salvaged with bedaquiline and clofazimine |
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Authors | |
Keywords | leukemia non-tuberculous Mycobacteria osteomyelitis |
Issue Date | 2021 |
Publisher | Elsevier, published in association with International Society for Infectious Diseases. The Journal's web site is located at http://www.elsevier.com/locate/ijid |
Citation | International Journal of Infectious Diseases, 2021, v. 103, p. 9-12 How to Cite? |
Abstract | Our patient was a 4-year-old female with acute myeloid leukemia complicated with right calcaneal osteomyelitis due to Mycobacterium abscessus with subcutaneous abscesses extending to the popliteal and groin regions after two courses of induction chemotherapy according to NOPHO-AML 2012 protocol. She required multiple operations and prolonged anti-mycobacterial therapy. A high index of suspicion for mycobacterial infection is required for immunocompromised patients with prolonged fever or unusual presentation. Mycobacterial osteomyelitis is rare, difficult to diagnose and treat, and may necessitate prolonged interruption of anti-leukemic therapy. Multidisciplinary collaboration in patient management is crucial. Long-term toxicity of antimicrobials with uncertain efficacy should not be overlooked. |
Persistent Identifier | http://hdl.handle.net/10722/307695 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.435 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, WYK | - |
dc.contributor.author | Ho, PL | - |
dc.contributor.author | To, KKW | - |
dc.contributor.author | Lam, AYL | - |
dc.contributor.author | Ho, KWY | - |
dc.contributor.author | Lau, TW | - |
dc.contributor.author | So, NLW | - |
dc.contributor.author | Ha, SY | - |
dc.date.accessioned | 2021-11-12T13:36:27Z | - |
dc.date.available | 2021-11-12T13:36:27Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | International Journal of Infectious Diseases, 2021, v. 103, p. 9-12 | - |
dc.identifier.issn | 1201-9712 | - |
dc.identifier.uri | http://hdl.handle.net/10722/307695 | - |
dc.description.abstract | Our patient was a 4-year-old female with acute myeloid leukemia complicated with right calcaneal osteomyelitis due to Mycobacterium abscessus with subcutaneous abscesses extending to the popliteal and groin regions after two courses of induction chemotherapy according to NOPHO-AML 2012 protocol. She required multiple operations and prolonged anti-mycobacterial therapy. A high index of suspicion for mycobacterial infection is required for immunocompromised patients with prolonged fever or unusual presentation. Mycobacterial osteomyelitis is rare, difficult to diagnose and treat, and may necessitate prolonged interruption of anti-leukemic therapy. Multidisciplinary collaboration in patient management is crucial. Long-term toxicity of antimicrobials with uncertain efficacy should not be overlooked. | - |
dc.language | eng | - |
dc.publisher | Elsevier, published in association with International Society for Infectious Diseases. The Journal's web site is located at http://www.elsevier.com/locate/ijid | - |
dc.relation.ispartof | International Journal of Infectious Diseases | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | leukemia | - |
dc.subject | non-tuberculous Mycobacteria | - |
dc.subject | osteomyelitis | - |
dc.title | A child with acute myeloid leukemia complicated by calcaneal osteomyelitis due to Mycobacterium abscessus infection after induction chemotherapy successfully salvaged with bedaquiline and clofazimine | - |
dc.type | Article | - |
dc.identifier.email | Ho, PL: plho@hku.hk | - |
dc.identifier.email | To, KKW: kelvinto@hku.hk | - |
dc.identifier.email | Lam, AYL: yllam1@hku.hk | - |
dc.identifier.email | Ho, KWY: howyk@hku.hk | - |
dc.identifier.email | Lau, TW: catcher@hkucc.hku.hk | - |
dc.identifier.email | So, NLW: noahso@hku.hk | - |
dc.identifier.email | Ha, SY: syha@hku.hk | - |
dc.identifier.authority | Ho, PL=rp00406 | - |
dc.identifier.authority | To, KKW=rp01384 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.ijid.2020.10.102 | - |
dc.identifier.pmid | 33160065 | - |
dc.identifier.scopus | eid_2-s2.0-85097743311 | - |
dc.identifier.hkuros | 329806 | - |
dc.identifier.volume | 103 | - |
dc.identifier.spage | 9 | - |
dc.identifier.epage | 12 | - |
dc.identifier.isi | WOS:000616676100004 | - |
dc.publisher.place | United Kingdom | - |