File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1021/acs.orglett.1c02699
- Scopus: eid_2-s2.0-85114686947
- PMID: 34428074
- WOS: WOS:000693633500076
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Iron-Catalyzed Highly Enantioselective Addition of Silyl Enol Ethers to α,β-Unsaturated 2-Acyl Imidazoles
| Title | Iron-Catalyzed Highly Enantioselective Addition of Silyl Enol Ethers to α,β-Unsaturated 2-Acyl Imidazoles |
|---|---|
| Authors | |
| Issue Date | 2021 |
| Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html |
| Citation | Organic Letters, 2021, v. 23 n. 17, p. 6993-6997 How to Cite? |
| Abstract | A chiral FeII(N4) complex (N4 = (R,R)-N,N′-bis(2-isopropylquinolin-8-yl)-1,2-diphenylethane-1,2-diamine) was developed for the asymmetric conjugate addition of silyl enol ethers, including both acyclic ones and cyclohexenone-derived ones, to α,β-unsaturated 2-acyl imidazoles. This FeII complex is an effective chiral Lewis acid and was applied in the synthesis of an array of chiral 1,5-dicarbonyl synthons and cyclohexenone derivatives with high yields and enantioselectivities (up to 99% ee). |
| Persistent Identifier | http://hdl.handle.net/10722/306352 |
| ISSN | 2021 Impact Factor: 6.072 2020 SCImago Journal Rankings: 1.940 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wei, J | - |
| dc.contributor.author | Huang, JS | - |
| dc.contributor.author | Che, CM | - |
| dc.date.accessioned | 2021-10-20T10:22:24Z | - |
| dc.date.available | 2021-10-20T10:22:24Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.citation | Organic Letters, 2021, v. 23 n. 17, p. 6993-6997 | - |
| dc.identifier.issn | 1523-7060 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/306352 | - |
| dc.description.abstract | A chiral FeII(N4) complex (N4 = (R,R)-N,N′-bis(2-isopropylquinolin-8-yl)-1,2-diphenylethane-1,2-diamine) was developed for the asymmetric conjugate addition of silyl enol ethers, including both acyclic ones and cyclohexenone-derived ones, to α,β-unsaturated 2-acyl imidazoles. This FeII complex is an effective chiral Lewis acid and was applied in the synthesis of an array of chiral 1,5-dicarbonyl synthons and cyclohexenone derivatives with high yields and enantioselectivities (up to 99% ee). | - |
| dc.language | eng | - |
| dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html | - |
| dc.relation.ispartof | Organic Letters | - |
| dc.title | Iron-Catalyzed Highly Enantioselective Addition of Silyl Enol Ethers to α,β-Unsaturated 2-Acyl Imidazoles | - |
| dc.type | Article | - |
| dc.identifier.email | Huang, JS: jshuang@hku.hk | - |
| dc.identifier.email | Che, CM: chemhead@hku.hk | - |
| dc.identifier.authority | Huang, JS=rp00709 | - |
| dc.identifier.authority | Che, CM=rp00670 | - |
| dc.description.nature | link_to_subscribed_fulltext | - |
| dc.identifier.doi | 10.1021/acs.orglett.1c02699 | - |
| dc.identifier.pmid | 34428074 | - |
| dc.identifier.scopus | eid_2-s2.0-85114686947 | - |
| dc.identifier.hkuros | 327857 | - |
| dc.identifier.volume | 23 | - |
| dc.identifier.issue | 17 | - |
| dc.identifier.spage | 6993 | - |
| dc.identifier.epage | 6997 | - |
| dc.identifier.isi | WOS:000693633500076 | - |
| dc.publisher.place | United States | - |