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Article: Nonspherical Metal‐Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity

TitleNonspherical Metal‐Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity
Authors
Keywordsbiological activity
immune response
metal-based nanoarchitectures
nonspherical nanoparticles
organ toxicity
Issue Date2021
PublisherWiley - VCH Verlag GmbH & Co KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jabout/107640323/2421_info.html
Citation
Small, 2021, v. 17 n. 17, p. article no. 2007073 How to Cite?
AbstractMetal-based nanoentities, apart from being indispensable research tools, have found extensive use in the industrial and biomedical arena. Because their biological impacts are governed by factors such as size, shape, and composition, such issues must be taken into account when these materials are incorporated into multi-component ensembles for clinical applications. The size and shape (rods, wires, sheets, tubes, and cages) of metallic nanostructures influence cell viability by virtue of their varied geometry and physicochemical interactions with mammalian cell membranes. The anisotropic properties of nonspherical metal-based nanoarchitectures render them exciting candidates for biomedical applications. Here, the size-, shape-, and composition-dependent properties of nonspherical metal-based nanoarchitectures are reviewed in the context of their potential applications in cancer diagnostics and therapeutics, as well as, in regenerative medicine. Strategies for the synthesis of nonspherical metal-based nanoarchitectures and their cytotoxicity and immunological profiles are also comprehensively appraised.
Persistent Identifierhttp://hdl.handle.net/10722/305263
ISSN
2023 Impact Factor: 13.0
2023 SCImago Journal Rankings: 3.348
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZare, EN-
dc.contributor.authorZheng, X-
dc.contributor.authorMakvandi, P-
dc.contributor.authorGheybi, H-
dc.contributor.authorSartorius, R-
dc.contributor.authorYiu, CKY-
dc.contributor.authorAdeli, M-
dc.contributor.authorWu, A-
dc.contributor.authorZarrabi, A-
dc.contributor.authorVarma, RS-
dc.contributor.authorTay, FR-
dc.date.accessioned2021-10-20T10:06:57Z-
dc.date.available2021-10-20T10:06:57Z-
dc.date.issued2021-
dc.identifier.citationSmall, 2021, v. 17 n. 17, p. article no. 2007073-
dc.identifier.issn1613-6810-
dc.identifier.urihttp://hdl.handle.net/10722/305263-
dc.description.abstractMetal-based nanoentities, apart from being indispensable research tools, have found extensive use in the industrial and biomedical arena. Because their biological impacts are governed by factors such as size, shape, and composition, such issues must be taken into account when these materials are incorporated into multi-component ensembles for clinical applications. The size and shape (rods, wires, sheets, tubes, and cages) of metallic nanostructures influence cell viability by virtue of their varied geometry and physicochemical interactions with mammalian cell membranes. The anisotropic properties of nonspherical metal-based nanoarchitectures render them exciting candidates for biomedical applications. Here, the size-, shape-, and composition-dependent properties of nonspherical metal-based nanoarchitectures are reviewed in the context of their potential applications in cancer diagnostics and therapeutics, as well as, in regenerative medicine. Strategies for the synthesis of nonspherical metal-based nanoarchitectures and their cytotoxicity and immunological profiles are also comprehensively appraised.-
dc.languageeng-
dc.publisherWiley - VCH Verlag GmbH & Co KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jabout/107640323/2421_info.html-
dc.relation.ispartofSmall-
dc.rightsSmall. Copyright © Wiley - VCH Verlag GmbH & Co KGaA.-
dc.rightsSubmitted (preprint) Version: This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions Accepted (peer-reviewed) Version: This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.-
dc.subjectbiological activity-
dc.subjectimmune response-
dc.subjectmetal-based nanoarchitectures-
dc.subjectnonspherical nanoparticles-
dc.subjectorgan toxicity-
dc.titleNonspherical Metal‐Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity-
dc.typeArticle-
dc.identifier.emailYiu, CKY: ckyyiu@hkucc.hku.hk-
dc.identifier.emailTay, FR: franktay@hkucc.hku.hk-
dc.identifier.authorityYiu, CKY=rp00018-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/smll.202007073-
dc.identifier.pmid33710754-
dc.identifier.scopuseid_2-s2.0-85102393118-
dc.identifier.hkuros328328-
dc.identifier.volume17-
dc.identifier.issue17-
dc.identifier.spagearticle no. 2007073-
dc.identifier.epagearticle no. 2007073-
dc.identifier.isiWOS:000627838900001-
dc.publisher.placeGermany-

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