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Article: Engineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning

TitleEngineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning
Authors
Jamaledin, RMakvandi, PYiu, CKYAgarwal, TVecchione, RSun, WMaiti, TKTay, FRNetti, PA
KeywordsControlled release
Drug delivery efficacy
Microneedles
Drug release mechanisms
Responsive microneedles
Transdermal patches
Issue Date2020
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2366-3987
Citation
Advanced Therapeutics, 2020, v. 3 n. 12, article no. 2000171 How to Cite?
DOI: http://dx.doi.org/10.1002/adtp.202000171
AbstractTransdermal microneedle patches have attracted significant attention in the medical arena over the last decade as alternatives to traditional drug delivery methods. Microneedle patches are capable of delivering their payloads using burst- and sustained-release mechanisms, or in response to internal/external triggers, to optimize their therapeutic potency. Herein, drug release mechanisms and profiles are reviewed, along with the impact of the cargo release on cytotoxicity and delivery efficacy. The potential applications of microneedles in transdermal treatment, from prophylaxis to therapeutics, are also highlighted.
Persistent Identifierhttp://hdl.handle.net/10722/305262
ISSN
2366-3987
2023 Impact Factor: 3.7
2023 SCImago Journal Rankings: 1.063
ISI Accession Number ID
WOS:000574641600001

 

DC FieldValueLanguage
dc.contributor.authorJamaledin, R-
dc.contributor.authorMakvandi, P-
dc.contributor.authorYiu, CKY-
dc.contributor.authorAgarwal, T-
dc.contributor.authorVecchione, R-
dc.contributor.authorSun, W-
dc.contributor.authorMaiti, TK-
dc.contributor.authorTay, FR-
dc.contributor.authorNetti, PA-
dc.date.accessioned2021-10-20T10:06:56Z-
dc.date.available2021-10-20T10:06:56Z-
dc.date.issued2020-
dc.identifier.citationAdvanced Therapeutics, 2020, v. 3 n. 12, article no. 2000171-
dc.identifier.issn2366-3987-
dc.identifier.urihttp://hdl.handle.net/10722/305262-
dc.description.abstractTransdermal microneedle patches have attracted significant attention in the medical arena over the last decade as alternatives to traditional drug delivery methods. Microneedle patches are capable of delivering their payloads using burst- and sustained-release mechanisms, or in response to internal/external triggers, to optimize their therapeutic potency. Herein, drug release mechanisms and profiles are reviewed, along with the impact of the cargo release on cytotoxicity and delivery efficacy. The potential applications of microneedles in transdermal treatment, from prophylaxis to therapeutics, are also highlighted.-
dc.languageeng-
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2366-3987-
dc.relation.ispartofAdvanced Therapeutics-
dc.subjectControlled release-
dc.subjectDrug delivery efficacy-
dc.subjectMicroneedles-
dc.subjectDrug release mechanisms-
dc.subjectResponsive microneedles-
dc.subjectTransdermal patches-
dc.titleEngineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning-
dc.typeArticle-
dc.identifier.emailYiu, CKY: ckyyiu@hkucc.hku.hk-
dc.identifier.authorityYiu, CKY=rp00018-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/adtp.202000171-
dc.identifier.scopuseid_2-s2.0-85100590734-
dc.identifier.hkuros328326-
dc.identifier.volume3-
dc.identifier.issue12-
dc.identifier.spagearticle no. 2000171-
dc.identifier.epagearticle no. 2000171-
dc.identifier.isiWOS:000574641600001-
dc.publisher.placeUnited Kingdom-

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