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- Publisher Website: 10.1002/adtp.202000171
- Scopus: eid_2-s2.0-85100590734
- WOS: WOS:000574641600001
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Article: Engineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning
Title | Engineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning |
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Authors | |
Keywords | Controlled release Drug delivery efficacy Microneedles Drug release mechanisms Responsive microneedles Transdermal patches |
Issue Date | 2020 |
Publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2366-3987 |
Citation | Advanced Therapeutics, 2020, v. 3 n. 12, article no. 2000171 How to Cite? |
Abstract | Transdermal microneedle patches have attracted significant attention in the medical arena over the last decade as alternatives to traditional drug delivery methods. Microneedle patches are capable of delivering their payloads using burst- and sustained-release mechanisms, or in response to internal/external triggers, to optimize their therapeutic potency. Herein, drug release mechanisms and profiles are reviewed, along with the impact of the cargo release on cytotoxicity and delivery efficacy. The potential applications of microneedles in transdermal treatment, from prophylaxis to therapeutics, are also highlighted. |
Persistent Identifier | http://hdl.handle.net/10722/305262 |
ISSN | 2023 Impact Factor: 3.7 2023 SCImago Journal Rankings: 1.063 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Jamaledin, R | - |
dc.contributor.author | Makvandi, P | - |
dc.contributor.author | Yiu, CKY | - |
dc.contributor.author | Agarwal, T | - |
dc.contributor.author | Vecchione, R | - |
dc.contributor.author | Sun, W | - |
dc.contributor.author | Maiti, TK | - |
dc.contributor.author | Tay, FR | - |
dc.contributor.author | Netti, PA | - |
dc.date.accessioned | 2021-10-20T10:06:56Z | - |
dc.date.available | 2021-10-20T10:06:56Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Advanced Therapeutics, 2020, v. 3 n. 12, article no. 2000171 | - |
dc.identifier.issn | 2366-3987 | - |
dc.identifier.uri | http://hdl.handle.net/10722/305262 | - |
dc.description.abstract | Transdermal microneedle patches have attracted significant attention in the medical arena over the last decade as alternatives to traditional drug delivery methods. Microneedle patches are capable of delivering their payloads using burst- and sustained-release mechanisms, or in response to internal/external triggers, to optimize their therapeutic potency. Herein, drug release mechanisms and profiles are reviewed, along with the impact of the cargo release on cytotoxicity and delivery efficacy. The potential applications of microneedles in transdermal treatment, from prophylaxis to therapeutics, are also highlighted. | - |
dc.language | eng | - |
dc.publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2366-3987 | - |
dc.relation.ispartof | Advanced Therapeutics | - |
dc.subject | Controlled release | - |
dc.subject | Drug delivery efficacy | - |
dc.subject | Microneedles | - |
dc.subject | Drug release mechanisms | - |
dc.subject | Responsive microneedles | - |
dc.subject | Transdermal patches | - |
dc.title | Engineered Microneedle Patches for Controlled Release of Active Compounds: Recent Advances in Release Profile Tuning | - |
dc.type | Article | - |
dc.identifier.email | Yiu, CKY: ckyyiu@hkucc.hku.hk | - |
dc.identifier.authority | Yiu, CKY=rp00018 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/adtp.202000171 | - |
dc.identifier.scopus | eid_2-s2.0-85100590734 | - |
dc.identifier.hkuros | 328326 | - |
dc.identifier.volume | 3 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | article no. 2000171 | - |
dc.identifier.epage | article no. 2000171 | - |
dc.identifier.isi | WOS:000574641600001 | - |
dc.publisher.place | United Kingdom | - |