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- Publisher Website: 10.1021/acsami.0c19465
- Scopus: eid_2-s2.0-85100238762
- PMID: 33480246
- WOS: WOS:000619638400002
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Article: Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV-2 via Solids
Title | Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV-2 via Solids |
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Authors | |
Keywords | SARS-CoV-2 coronavirus coating CuO cupric oxide viricidal |
Issue Date | 2021 |
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick |
Citation | ACS Applied Materials & Interfaces, 2021, v. 13 n. 5, p. 5919-5928 How to Cite? |
Abstract | The ongoing COVID-19 pandemic has created a need for coatings that reduce infection from SARS-CoV-2 via surfaces. Such a coating could be used on common touch surfaces (e.g., door handles and railings) to reduce both disease transmission and fear of touching objects. Herein, we describe the design, fabrication, and testing of a cupric oxide anti-SARS-CoV-2 coating. Rapid loss of infectivity is an important design criterion, so a porous hydrophilic coating was created to allow rapid infiltration of aqueous solutions into the coating where diffusion distances to the cupric oxide surface are short and the surface area is large. The coating was deposited onto glass from a dispersion of cuprous oxide in ethanol and then thermally treated at 700 °C for 2 h to produce a CuO coating that is ≈30 μm thick. The heat treatment oxidized the cuprous oxide to cupric oxide and sintered the particles into a robust film. The SARS-CoV-2 infectivity from the CuO film was reduced by 99.8% in 30 min and 99.9% in 1 h compared to that from glass. The coating remained hydrophilic for at least 5 months, and there was no significant change in the cross-hatch test of robustness after exposure to 70% ethanol or 3 wt % bleach. |
Persistent Identifier | http://hdl.handle.net/10722/305234 |
ISSN | 2023 Impact Factor: 8.3 2023 SCImago Journal Rankings: 2.058 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Hosseini, M | - |
dc.contributor.author | Chin, AWH | - |
dc.contributor.author | Behzadinasab, S | - |
dc.contributor.author | Poon, LLM | - |
dc.contributor.author | Ducker, WA | - |
dc.date.accessioned | 2021-10-20T10:06:32Z | - |
dc.date.available | 2021-10-20T10:06:32Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | ACS Applied Materials & Interfaces, 2021, v. 13 n. 5, p. 5919-5928 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | http://hdl.handle.net/10722/305234 | - |
dc.description.abstract | The ongoing COVID-19 pandemic has created a need for coatings that reduce infection from SARS-CoV-2 via surfaces. Such a coating could be used on common touch surfaces (e.g., door handles and railings) to reduce both disease transmission and fear of touching objects. Herein, we describe the design, fabrication, and testing of a cupric oxide anti-SARS-CoV-2 coating. Rapid loss of infectivity is an important design criterion, so a porous hydrophilic coating was created to allow rapid infiltration of aqueous solutions into the coating where diffusion distances to the cupric oxide surface are short and the surface area is large. The coating was deposited onto glass from a dispersion of cuprous oxide in ethanol and then thermally treated at 700 °C for 2 h to produce a CuO coating that is ≈30 μm thick. The heat treatment oxidized the cuprous oxide to cupric oxide and sintered the particles into a robust film. The SARS-CoV-2 infectivity from the CuO film was reduced by 99.8% in 30 min and 99.9% in 1 h compared to that from glass. The coating remained hydrophilic for at least 5 months, and there was no significant change in the cross-hatch test of robustness after exposure to 70% ethanol or 3 wt % bleach. | - |
dc.language | eng | - |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/aamick | - |
dc.relation.ispartof | ACS Applied Materials & Interfaces | - |
dc.rights | This document is the Accepted Manuscript version of a Published Work that appeared in final form in [JournalTitle], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://pubs.acs.org/page/policy/articlesonrequest/index.html]. | - |
dc.subject | SARS-CoV-2 | - |
dc.subject | coronavirus | - |
dc.subject | coating | - |
dc.subject | CuO cupric oxide | - |
dc.subject | viricidal | - |
dc.title | Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV-2 via Solids | - |
dc.type | Article | - |
dc.identifier.email | Chin, AWH: alexchin@hku.hk | - |
dc.identifier.email | Poon, LLM: llmpoon@hkucc.hku.hk | - |
dc.identifier.authority | Chin, AWH=rp02345 | - |
dc.identifier.authority | Poon, LLM=rp00484 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1021/acsami.0c19465 | - |
dc.identifier.pmid | 33480246 | - |
dc.identifier.pmcid | PMC7857137 | - |
dc.identifier.scopus | eid_2-s2.0-85100238762 | - |
dc.identifier.hkuros | 327089 | - |
dc.identifier.volume | 13 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 5919 | - |
dc.identifier.epage | 5928 | - |
dc.identifier.isi | WOS:000619638400002 | - |
dc.publisher.place | United States | - |