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Article: Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 Virus Variant With Novel Genomic Architecture in Hong Kong

TitleEmergence of a Severe Acute Respiratory Syndrome Coronavirus 2 Virus Variant With Novel Genomic Architecture in Hong Kong
Authors
Tse, HLung, DCWong, SCYIp, KFWu, TCTo, KKWKok, KHYuen, KYChoi, GKY
KeywordsCOVID-19
SARS-CoV-2
Whole-genome sequencing
Genomic rearrangement
Issue Date2021
PublisherOxford University Press, published in association with Clinical Infectious Diseases. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/
Citation
Clinical Infectious Diseases, 2021, v. 73 n. 9, p. 1696-1699 How to Cite?
DOI: http://dx.doi.org/10.1093/cid/ciab198
AbstractThroughout the coronavirus disease 2019 (COVID-19) pandemic, divergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages have emerged continuously, mostly through the genomic accumulation of substitutions. We report the discovery of a SARS-CoV-2 variant with a novel genomic architecture characterized by absent ORF7a, ORF7b, and ORF8, and a C-terminally modified ORF6 product resulting from partial 5′-untranslated region (UTR) duplication and transposition.
Persistent Identifierhttp://hdl.handle.net/10722/304719
ISSN
1058-4838
2021 Impact Factor: 20.999
2020 SCImago Journal Rankings: 3.440
PubMed Central ID
PMC7989571
ISI Accession Number ID
WOS:000720749600214

 

DC FieldValueLanguage
dc.contributor.authorTse, H-
dc.contributor.authorLung, DC-
dc.contributor.authorWong, SCY-
dc.contributor.authorIp, KF-
dc.contributor.authorWu, TC-
dc.contributor.authorTo, KKW-
dc.contributor.authorKok, KH-
dc.contributor.authorYuen, KY-
dc.contributor.authorChoi, GKY-
dc.date.accessioned2021-10-05T02:34:11Z-
dc.date.available2021-10-05T02:34:11Z-
dc.date.issued2021-
dc.identifier.citationClinical Infectious Diseases, 2021, v. 73 n. 9, p. 1696-1699-
dc.identifier.issn1058-4838-
dc.identifier.urihttp://hdl.handle.net/10722/304719-
dc.description.abstractThroughout the coronavirus disease 2019 (COVID-19) pandemic, divergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages have emerged continuously, mostly through the genomic accumulation of substitutions. We report the discovery of a SARS-CoV-2 variant with a novel genomic architecture characterized by absent ORF7a, ORF7b, and ORF8, and a C-terminally modified ORF6 product resulting from partial 5′-untranslated region (UTR) duplication and transposition.-
dc.languageeng-
dc.publisherOxford University Press, published in association with Clinical Infectious Diseases. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/-
dc.relation.ispartofClinical Infectious Diseases-
dc.subjectCOVID-19-
dc.subjectSARS-CoV-2-
dc.subjectWhole-genome sequencing-
dc.subjectGenomic rearrangement-
dc.titleEmergence of a Severe Acute Respiratory Syndrome Coronavirus 2 Virus Variant With Novel Genomic Architecture in Hong Kong-
dc.typeArticle-
dc.identifier.emailTo, KKW: kelvinto@hku.hk-
dc.identifier.emailKok, KH: khkok@hku.hk-
dc.identifier.emailYuen, KY: kyyuen@hkucc.hku.hk-
dc.identifier.authorityTse, H=rp00519-
dc.identifier.authorityTo, KKW=rp01384-
dc.identifier.authorityKok, KH=rp01455-
dc.identifier.authorityYuen, KY=rp00366-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/cid/ciab198-
dc.identifier.pmid33675655-
dc.identifier.pmcidPMC7989571-
dc.identifier.scopuseid_2-s2.0-85104469003-
dc.identifier.hkuros326100-
dc.identifier.volume73-
dc.identifier.issue9-
dc.identifier.spage1696-
dc.identifier.epage1699-
dc.identifier.isiWOS:000720749600214-
dc.publisher.placeUnited States-

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