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Article: Self-Assembled PHMB Titanium Coating Enables Anti-Fusobacterium nucleatum Strategy
Title | Self-Assembled PHMB Titanium Coating Enables Anti-Fusobacterium nucleatum Strategy |
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Authors | |
Keywords | Polyhexamethylene biguanide Titanium dental implant Peri-implantitis Antimicrobial |
Issue Date | 2021 |
Publisher | MDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/coatings |
Citation | Coatings, 2021, v. 11 n. 10, article no. 1190 How to Cite? |
Abstract | Fusobacterium nucleatum (F. nucleatum) is a gram-negative obligate anaerobe bacterium that threatens human periodontal health. It can cause many oral diseases, including periodontitis, gingivitis and peri-implantitis, and even some diseases such as colorectal cancer are related to it. This paper aims to develop a novel and simple surface modification method for anti-Fusobacterium nucleatum on titanium, i.e., the material for implants. In this study, different concentrations (0.0–1.0%) of PHMB were dip-coated on the titanium surface. The surface properties were examined with the aid of Scanning electron microscopy, Energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy, and the antibacterial property against F. nucleatum was investigated using colony-forming unit. It was found that the PHMB successfully formed a self-assembled coating on the titanium surface and the PHMB-coated titanium had a strong capability of inhibiting F. nucleatum. Even though differences were found among the several concentrations, PHMB exhibited promising results as a simple coating strategy for dental implants. |
Persistent Identifier | http://hdl.handle.net/10722/304647 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.493 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Zhao, J | - |
dc.contributor.author | Jin, S | - |
dc.contributor.author | Delgado, AHS | - |
dc.contributor.author | Chen, Z | - |
dc.contributor.author | Matinlinna, JP | - |
dc.contributor.author | Tsoi, JKH | - |
dc.date.accessioned | 2021-10-05T02:33:09Z | - |
dc.date.available | 2021-10-05T02:33:09Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Coatings, 2021, v. 11 n. 10, article no. 1190 | - |
dc.identifier.issn | 2079-6412 | - |
dc.identifier.uri | http://hdl.handle.net/10722/304647 | - |
dc.description.abstract | Fusobacterium nucleatum (F. nucleatum) is a gram-negative obligate anaerobe bacterium that threatens human periodontal health. It can cause many oral diseases, including periodontitis, gingivitis and peri-implantitis, and even some diseases such as colorectal cancer are related to it. This paper aims to develop a novel and simple surface modification method for anti-Fusobacterium nucleatum on titanium, i.e., the material for implants. In this study, different concentrations (0.0–1.0%) of PHMB were dip-coated on the titanium surface. The surface properties were examined with the aid of Scanning electron microscopy, Energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy, and the antibacterial property against F. nucleatum was investigated using colony-forming unit. It was found that the PHMB successfully formed a self-assembled coating on the titanium surface and the PHMB-coated titanium had a strong capability of inhibiting F. nucleatum. Even though differences were found among the several concentrations, PHMB exhibited promising results as a simple coating strategy for dental implants. | - |
dc.language | eng | - |
dc.publisher | MDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/coatings | - |
dc.relation.ispartof | Coatings | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Polyhexamethylene biguanide | - |
dc.subject | Titanium dental implant | - |
dc.subject | Peri-implantitis | - |
dc.subject | Antimicrobial | - |
dc.title | Self-Assembled PHMB Titanium Coating Enables Anti-Fusobacterium nucleatum Strategy | - |
dc.type | Article | - |
dc.identifier.email | Matinlinna, JP: jpmat@hku.hk | - |
dc.identifier.email | Tsoi, JKH: jkhtsoi@hku.hk | - |
dc.identifier.authority | Matinlinna, JP=rp00052 | - |
dc.identifier.authority | Tsoi, JKH=rp01609 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3390/coatings11101190 | - |
dc.identifier.scopus | eid_2-s2.0-85116427835 | - |
dc.identifier.hkuros | 326564 | - |
dc.identifier.volume | 11 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | article no. 1190 | - |
dc.identifier.epage | article no. 1190 | - |
dc.identifier.isi | WOS:000711367400001 | - |
dc.publisher.place | Switzerland | - |