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Article: Five Challenges in the Field of Viral Diversity and Evolution
Title | Five Challenges in the Field of Viral Diversity and Evolution |
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Authors | |
Keywords | virus evolution viral metagenomics viral phylogenetics viral emergence evolutionary predictability |
Issue Date | 2021 |
Publisher | Frontiers Media SA. The Journal's web site is located at https://www.frontiersin.org/journals/virology |
Citation | Frontiers in Virology, 2021, v. 1, p. article no. 684949 How to Cite? |
Abstract | Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes. |
Persistent Identifier | http://hdl.handle.net/10722/304594 |
DC Field | Value | Language |
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dc.contributor.author | Sanjuan, R | - |
dc.contributor.author | Illingworth, CJR | - |
dc.contributor.author | Geoghegan, JL | - |
dc.contributor.author | Iranzo, J | - |
dc.contributor.author | Zwart, MP | - |
dc.contributor.author | Ciota, AT | - |
dc.contributor.author | Moratorio, G | - |
dc.contributor.author | Gago-Zachert, S | - |
dc.contributor.author | Duffy, S | - |
dc.contributor.author | Dhanasekaran, V | - |
dc.date.accessioned | 2021-10-05T02:32:23Z | - |
dc.date.available | 2021-10-05T02:32:23Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Frontiers in Virology, 2021, v. 1, p. article no. 684949 | - |
dc.identifier.uri | http://hdl.handle.net/10722/304594 | - |
dc.description.abstract | Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes. | - |
dc.language | eng | - |
dc.publisher | Frontiers Media SA. The Journal's web site is located at https://www.frontiersin.org/journals/virology | - |
dc.relation.ispartof | Frontiers in Virology | - |
dc.rights | This Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | virus evolution | - |
dc.subject | viral metagenomics | - |
dc.subject | viral phylogenetics | - |
dc.subject | viral emergence | - |
dc.subject | evolutionary predictability | - |
dc.title | Five Challenges in the Field of Viral Diversity and Evolution | - |
dc.type | Article | - |
dc.identifier.email | Dhanasekaran, V: veej@hku.hk | - |
dc.identifier.authority | Dhanasekaran, V=rp02721 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3389/fviro.2021.684949 | - |
dc.identifier.hkuros | 325793 | - |
dc.identifier.volume | 1 | - |
dc.identifier.spage | article no. 684949 | - |
dc.identifier.epage | article no. 684949 | - |
dc.identifier.eissn | 2673-818X | - |
dc.publisher.place | Switzerland | - |