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Conference Paper: The prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis
| Title | The prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis |
|---|---|
| Authors | |
| Issue Date | 2019 |
| Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom |
| Citation | The 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), Rio de Janeiro, Brazil, 21-24 May 2019. In International Journal of Oral and Maxillofacial Surgery, 2019, v. 48 n. Suppl. 1, p. 76 How to Cite? |
| Abstract | Background: Human papilloma virus (HPV) infection has been confirmed as a favorable prognostic factor in oropharyngeal cancer. However, the prognostic value of HPV in oral cavity squamous cell carcinoma is still unclear.
Objectives: This study aimed to review all published articles and conduct a meta-analysis on the overall survival (OS), diseases free survival (DFS), and diseases specific survival (DSS) of HPV positive and negative HPV oral cavity squamous cell carcinoma.
Methods: A systematic literature review was conducted in accordance with PRISMA statement checklist and flowchart in PubMed, EMBASE, and MEDLINE databases.
Findings: A total of seventeen articles were included in this study. The hazard ratio (HR) for OS, DFS, and DSS comparing HPV positive and negative oral cavity squamous cell carcinoma were 1.47(95% CI = 0.98-2.22), 1.22(95% CI = 0.81-1.84), and 0.96 (95% CI = 0.50-1.87) respectively, suggesting no significant difference detected.
Conclusion: Our results showed there was no significant difference in OS, DFS, and DSS between HPV-positive and negative oral cavity cancer patients. Therefore, HPV infection is not a prognostic factor for oral cavity squamous cell carcinoma. |
| Description | Free Paper Oral Presentation - Head and Neck Oncology |
| Persistent Identifier | http://hdl.handle.net/10722/302488 |
| ISSN | 2021 Impact Factor: 2.986 2020 SCImago Journal Rankings: 1.020 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Christianto, S | - |
| dc.contributor.author | Li, KY | - |
| dc.contributor.author | Huang, TH | - |
| dc.contributor.author | Su, Y | - |
| dc.date.accessioned | 2021-09-06T03:33:01Z | - |
| dc.date.available | 2021-09-06T03:33:01Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | The 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), Rio de Janeiro, Brazil, 21-24 May 2019. In International Journal of Oral and Maxillofacial Surgery, 2019, v. 48 n. Suppl. 1, p. 76 | - |
| dc.identifier.issn | 0901-5027 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/302488 | - |
| dc.description | Free Paper Oral Presentation - Head and Neck Oncology | - |
| dc.description.abstract | Background: Human papilloma virus (HPV) infection has been confirmed as a favorable prognostic factor in oropharyngeal cancer. However, the prognostic value of HPV in oral cavity squamous cell carcinoma is still unclear. Objectives: This study aimed to review all published articles and conduct a meta-analysis on the overall survival (OS), diseases free survival (DFS), and diseases specific survival (DSS) of HPV positive and negative HPV oral cavity squamous cell carcinoma. Methods: A systematic literature review was conducted in accordance with PRISMA statement checklist and flowchart in PubMed, EMBASE, and MEDLINE databases. Findings: A total of seventeen articles were included in this study. The hazard ratio (HR) for OS, DFS, and DSS comparing HPV positive and negative oral cavity squamous cell carcinoma were 1.47(95% CI = 0.98-2.22), 1.22(95% CI = 0.81-1.84), and 0.96 (95% CI = 0.50-1.87) respectively, suggesting no significant difference detected. Conclusion: Our results showed there was no significant difference in OS, DFS, and DSS between HPV-positive and negative oral cavity cancer patients. Therefore, HPV infection is not a prognostic factor for oral cavity squamous cell carcinoma. | - |
| dc.language | eng | - |
| dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijom | - |
| dc.relation.ispartof | International Journal of Oral and Maxillofacial Surgery | - |
| dc.relation.ispartof | The 24th International Conference on Oral and Maxillofacial Surgery (ICOMS), 2019 | - |
| dc.title | The prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a systematic review and meta-analysis | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Su, Y: richsu@hku.hk | - |
| dc.identifier.authority | Su, Y=rp01916 | - |
| dc.description.nature | abstract | - |
| dc.identifier.doi | 10.1016/j.ijom.2019.03.228 | - |
| dc.identifier.hkuros | 324662 | - |
| dc.identifier.volume | 48 | - |
| dc.identifier.issue | Suppl. 1 | - |
| dc.identifier.spage | 76 | - |
| dc.identifier.epage | 76 | - |
| dc.publisher.place | United Kingdom | - |