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Article: Climatic modification effects on the association between PM1 and lung cancer incidence in China
Title | Climatic modification effects on the association between PM1 and lung cancer incidence in China |
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Authors | |
Keywords | Modification effects Climatic factors PM1 pollution Lung cancer incidence |
Issue Date | 2021 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/ |
Citation | BMC Public Health, 2021, v. 21, p. article no. 880 How to Cite? |
Abstract | Background:
Nationwide studies that examine climatic modification effects on the association between air pollution and health outcome are limited in developing countries. Moreover, few studies focus on PM1 pollution despite its greater health effect.
Objectives:
This study aims to determine the modification effects of climatic factors on the associations between PM1 and the incidence rates of lung cancer for males and females in China.
Methods:
We conducted a nationwide analysis in 345 Chinese counties (districts) from 2014 to 2015. Mean air temperature and relative humidity over the study period were used as the proxies of climatic conditions. In terms of the multivariable linear regression model, we examined climatic modification effects in the stratified and combined datasets according to the three-category and binary divisions of climatic factors. Moreover, we performed three sensitivity analyses to test the robustness of climatic modification effects.
Results:
We found a stronger association between PM1 and the incidence rate of male lung cancer in counties with high levels of air temperature or relative humidity. If there is a 10 μg/m3 shift in PM1, then the change in male incidence rate relative to its mean was higher by 4.39% (95% CI: 2.19, 6.58%) and 8.37% (95% CI: 5.18, 11.56%) in the middle and high temperature groups than in the low temperature group, respectively. The findings of climatic modification effects were robust in the three sensitivity analyses. No significant modification effect was discovered for female incidence rate.
Conclusions:
Male residents in high temperature or humidity counties suffer from a larger effect of PM1 on the incidence rate of lung cancer in China. Future research on air pollution-related health impact assessment should consider the differential air pollution effects across different climatic conditions. |
Persistent Identifier | http://hdl.handle.net/10722/300900 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 1.253 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Guo, H | - |
dc.contributor.author | Li, X | - |
dc.contributor.author | Li, W | - |
dc.contributor.author | Wu, J | - |
dc.contributor.author | WANG, S | - |
dc.contributor.author | Wei, J | - |
dc.date.accessioned | 2021-07-06T03:11:46Z | - |
dc.date.available | 2021-07-06T03:11:46Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | BMC Public Health, 2021, v. 21, p. article no. 880 | - |
dc.identifier.issn | 1471-2458 | - |
dc.identifier.uri | http://hdl.handle.net/10722/300900 | - |
dc.description.abstract | Background: Nationwide studies that examine climatic modification effects on the association between air pollution and health outcome are limited in developing countries. Moreover, few studies focus on PM1 pollution despite its greater health effect. Objectives: This study aims to determine the modification effects of climatic factors on the associations between PM1 and the incidence rates of lung cancer for males and females in China. Methods: We conducted a nationwide analysis in 345 Chinese counties (districts) from 2014 to 2015. Mean air temperature and relative humidity over the study period were used as the proxies of climatic conditions. In terms of the multivariable linear regression model, we examined climatic modification effects in the stratified and combined datasets according to the three-category and binary divisions of climatic factors. Moreover, we performed three sensitivity analyses to test the robustness of climatic modification effects. Results: We found a stronger association between PM1 and the incidence rate of male lung cancer in counties with high levels of air temperature or relative humidity. If there is a 10 μg/m3 shift in PM1, then the change in male incidence rate relative to its mean was higher by 4.39% (95% CI: 2.19, 6.58%) and 8.37% (95% CI: 5.18, 11.56%) in the middle and high temperature groups than in the low temperature group, respectively. The findings of climatic modification effects were robust in the three sensitivity analyses. No significant modification effect was discovered for female incidence rate. Conclusions: Male residents in high temperature or humidity counties suffer from a larger effect of PM1 on the incidence rate of lung cancer in China. Future research on air pollution-related health impact assessment should consider the differential air pollution effects across different climatic conditions. | - |
dc.language | eng | - |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/ | - |
dc.relation.ispartof | BMC Public Health | - |
dc.rights | BMC Public Health. Copyright © BioMed Central Ltd. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Modification effects | - |
dc.subject | Climatic factors | - |
dc.subject | PM1 pollution | - |
dc.subject | Lung cancer incidence | - |
dc.title | Climatic modification effects on the association between PM1 and lung cancer incidence in China | - |
dc.type | Article | - |
dc.identifier.email | Li, W: wfli@hku.hk | - |
dc.identifier.authority | Li, W=rp01507 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/s12889-021-10912-8 | - |
dc.identifier.scopus | eid_2-s2.0-85105446517 | - |
dc.identifier.hkuros | 323293 | - |
dc.identifier.volume | 21 | - |
dc.identifier.spage | article no. 880 | - |
dc.identifier.epage | article no. 880 | - |
dc.identifier.isi | WOS:000656235500004 | - |
dc.publisher.place | United Kingdom | - |