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Article: Feasibility study of a single-use balloon-assisted robotic colonoscope in healthy volunteers

TitleFeasibility study of a single-use balloon-assisted robotic colonoscope in healthy volunteers
Authors
Issue Date2021
PublisherThieme Open. The Journal's web site is located at https://www.thieme-connect.de/products/ejournals/journal/10.1055/s-00025476
Citation
Endoscopy International Open, 2021, v. 09 n. 04, p. E537-E542 How to Cite?
AbstractBackground and study aims: Despite its widespread adoption, colonoscope still has its limitations. Advancement is often limited by the looping of colon. The isolation of SARS-CoV-2 in stool raises concern for the risk of disease transmission. A single-use robotic colonoscope, the NISInspire-C System, that features a balloon-suction anchorage mechanism was developed to address these. Methods: The NISInspire-C balloons are designed to provide anchorage for straightening of the colon during advancement. Angulation at the bending section is tendon-wire driven by servo mechanisms integrated into a robotic control console. This was a pilot, prospective trial to evaluate the safety and feasibility of this system. Healthy volunteers underwent examination with the NISInspire-C, followed by the conventional colonoscope. The procedure time, cecal intubation rates (CIR), complications, and level of pain were measured. Results: A total of 19 subjects underwent the examination. The cecal intubation rate was 89.5 % (17/19) and the overall time-to-cecum was 26.3 minutes (SD: 17.9 mins). There were no procedure-related complications. Polyps were detected in seven of 19 (36.8 %) subjects during the NISInspire-C procedure. Three more subjects were found to have adenomatous polyps with the conventional colonoscope. There was minimal variation in level of pain during the procedures with the two colonoscopes. Conclusion: The single-use robotic colonoscope NISInspire-C is a safe and feasible alternative to the conventional colonoscope. Further technical refinement is needed to improve the CIR. This study was limited by its small sample size.
Persistent Identifierhttp://hdl.handle.net/10722/298709
ISSN
2020 SCImago Journal Rankings: 0.108
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorFoo, CC-
dc.contributor.authorLeung, WK-
dc.contributor.authorLui, TKL-
dc.contributor.authorCheung, JLK-
dc.contributor.authorLam, KW-
dc.contributor.authorSreedhar, B-
dc.contributor.authorYeung, CK-
dc.date.accessioned2021-04-12T03:02:18Z-
dc.date.available2021-04-12T03:02:18Z-
dc.date.issued2021-
dc.identifier.citationEndoscopy International Open, 2021, v. 09 n. 04, p. E537-E542-
dc.identifier.issn2364-3722-
dc.identifier.urihttp://hdl.handle.net/10722/298709-
dc.description.abstractBackground and study aims: Despite its widespread adoption, colonoscope still has its limitations. Advancement is often limited by the looping of colon. The isolation of SARS-CoV-2 in stool raises concern for the risk of disease transmission. A single-use robotic colonoscope, the NISInspire-C System, that features a balloon-suction anchorage mechanism was developed to address these. Methods: The NISInspire-C balloons are designed to provide anchorage for straightening of the colon during advancement. Angulation at the bending section is tendon-wire driven by servo mechanisms integrated into a robotic control console. This was a pilot, prospective trial to evaluate the safety and feasibility of this system. Healthy volunteers underwent examination with the NISInspire-C, followed by the conventional colonoscope. The procedure time, cecal intubation rates (CIR), complications, and level of pain were measured. Results: A total of 19 subjects underwent the examination. The cecal intubation rate was 89.5 % (17/19) and the overall time-to-cecum was 26.3 minutes (SD: 17.9 mins). There were no procedure-related complications. Polyps were detected in seven of 19 (36.8 %) subjects during the NISInspire-C procedure. Three more subjects were found to have adenomatous polyps with the conventional colonoscope. There was minimal variation in level of pain during the procedures with the two colonoscopes. Conclusion: The single-use robotic colonoscope NISInspire-C is a safe and feasible alternative to the conventional colonoscope. Further technical refinement is needed to improve the CIR. This study was limited by its small sample size.-
dc.languageeng-
dc.publisherThieme Open. The Journal's web site is located at https://www.thieme-connect.de/products/ejournals/journal/10.1055/s-00025476-
dc.relation.ispartofEndoscopy International Open-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleFeasibility study of a single-use balloon-assisted robotic colonoscope in healthy volunteers-
dc.typeArticle-
dc.identifier.emailFoo, CC: ccfoo@hku.hk-
dc.identifier.emailLeung, WK: waikleung@hku.hk-
dc.identifier.emailLui, TKL: lkl484@hku.hk-
dc.identifier.emailLam, KW: tkwlam@HKUCC-COM.hku.hk-
dc.identifier.authorityFoo, CC=rp01899-
dc.identifier.authorityLeung, WK=rp01479-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1055/a-1352-3688-
dc.identifier.pmid33816774-
dc.identifier.pmcidPMC7969132-
dc.identifier.hkuros322080-
dc.identifier.volume09-
dc.identifier.issue04-
dc.identifier.spageE537-
dc.identifier.epageE542-
dc.publisher.placeGermany-

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