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Conference Paper: The role of the brain in the adaptation to climate change

TitleThe role of the brain in the adaptation to climate change
Authors
Issue Date2017
PublisherSpringer New York LLC.
Citation
The 23rd Scientific Conference of the Society on Neuroimmune Pharmacology (SNIP), Philadelphia, PA, USA, 29 March - 1 April 2017. Abstracts in Journal of Neuroimmune Pharmacology, 2017, v. 12 n. Suppl. 1, p. 20-21 How to Cite?
AbstractThe increase of CO2 in the oceans, termed ocean acidification, is projected to have detrimental effects on marine organisms. The magnitude of the impact on the marine ecosystems will depend on species capacity to adapt. Recent studies show that the behaviour of reef fishes is impaired at projected CO2 levels; however, individual variation exists that might promote adaptation. Offspring of CO2-tolerant and CO2-sensitive parents were reared at nearfuture CO2 (754 uatm) or present-day control levels (414 uatm) and exposed to higher levels of CO2 at different life stages. We study the transcriptomes and proteomes in the brain of Acanthochromis polyacanthus (spiny damselfish), to evaluate short-term, longterm (one generation) and transgenerational molecular responses to more acidified oceans. Withingeneration CO2 exposure lead to an increased expression of genes involved in GABAergic neurotransmission as well as the potassium-chloride cotransporter 2 (kcc2). The reversal of the transmembrane gradient for HCO3- and Cl- with elevated levels of extracellular bicarbonate is the likely cause for the excitement of the neuronal transmission which in turn causes the behavioural impairment in fish at near-future high CO2 levels. We find a clear signature of the parental sensitivity to CO2 in the molecular phenotype of the offspring, mainly driven by circadian rhythm genes. Furthermore, expression patterns with prior parental CO2 acclimation largely differ to short-term or long-term exposures emphasizing the importance of transgenerational acclimation in exposure experiments.
DescriptionSymposium 8: Computational and Systems Biology Applied to the Brain
Persistent Identifierhttp://hdl.handle.net/10722/298620
ISSN
2019 Impact Factor: 4.113
2015 SCImago Journal Rankings: 1.662

 

DC FieldValueLanguage
dc.contributor.authorSchunter, CM-
dc.contributor.authorRavasi, T-
dc.date.accessioned2021-04-08T07:43:34Z-
dc.date.available2021-04-08T07:43:34Z-
dc.date.issued2017-
dc.identifier.citationThe 23rd Scientific Conference of the Society on Neuroimmune Pharmacology (SNIP), Philadelphia, PA, USA, 29 March - 1 April 2017. Abstracts in Journal of Neuroimmune Pharmacology, 2017, v. 12 n. Suppl. 1, p. 20-21-
dc.identifier.issn1557-1890-
dc.identifier.urihttp://hdl.handle.net/10722/298620-
dc.descriptionSymposium 8: Computational and Systems Biology Applied to the Brain-
dc.description.abstractThe increase of CO2 in the oceans, termed ocean acidification, is projected to have detrimental effects on marine organisms. The magnitude of the impact on the marine ecosystems will depend on species capacity to adapt. Recent studies show that the behaviour of reef fishes is impaired at projected CO2 levels; however, individual variation exists that might promote adaptation. Offspring of CO2-tolerant and CO2-sensitive parents were reared at nearfuture CO2 (754 uatm) or present-day control levels (414 uatm) and exposed to higher levels of CO2 at different life stages. We study the transcriptomes and proteomes in the brain of Acanthochromis polyacanthus (spiny damselfish), to evaluate short-term, longterm (one generation) and transgenerational molecular responses to more acidified oceans. Withingeneration CO2 exposure lead to an increased expression of genes involved in GABAergic neurotransmission as well as the potassium-chloride cotransporter 2 (kcc2). The reversal of the transmembrane gradient for HCO3- and Cl- with elevated levels of extracellular bicarbonate is the likely cause for the excitement of the neuronal transmission which in turn causes the behavioural impairment in fish at near-future high CO2 levels. We find a clear signature of the parental sensitivity to CO2 in the molecular phenotype of the offspring, mainly driven by circadian rhythm genes. Furthermore, expression patterns with prior parental CO2 acclimation largely differ to short-term or long-term exposures emphasizing the importance of transgenerational acclimation in exposure experiments.-
dc.languageeng-
dc.publisherSpringer New York LLC.-
dc.relation.ispartofJournal of Neuroimmune Pharmacology-
dc.relation.ispartofSociety on NeuroImmune Pharmacology Scientific Conference 2017-
dc.titleThe role of the brain in the adaptation to climate change-
dc.typeConference_Paper-
dc.identifier.emailSchunter, CM: schunter@hku.hk-
dc.identifier.authoritySchunter, CM=rp02465-
dc.description.natureabstract-
dc.identifier.hkuros301979-
dc.identifier.volume12-
dc.identifier.issueSuppl. 1-
dc.identifier.spage20-
dc.identifier.epage21-
dc.publisher.placeUnited States-
dc.identifier.partofdoi10.1007/s11481-017-9731-z-
dc.identifier.issnl1557-1890-

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