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Article: Label-free detection of DNA hybridization using transistors based on CVD grown graphene

TitleLabel-free detection of DNA hybridization using transistors based on CVD grown graphene
Authors
KeywordsDNA sensing
Gold-transfer method
Liquid-gated transistors
Label-free detection
CVD graphene
Issue Date2013
Citation
Biosensors and Bioelectronics, 2013, v. 41, n. 1, p. 103-109 How to Cite?
AbstractThe high transconductance and low noise of graphene-based field-effect transistors based on large-area monolayer graphene produced by chemical vapor deposition are used for label-free electrical detection of DNA hybridization. The gate materials, buffer concentration and surface condition of graphene have been optimized to achieve the DNA detection sensitivity as low as 1pM (10 M), which is more sensitive than the existing report based on few-layer graphene. The graphene films obtained using conventional PMMA-assisted transfer technique exhibits PMMA residues, which degrade the sensing performance of graphene. We have demonstrated that the sensing performance of the graphene samples prepared by gold-transfer is largely enhanced (by 125%). © 2012 Elsevier B.V. -12
Persistent Identifierhttp://hdl.handle.net/10722/298579
ISSN
2023 Impact Factor: 10.7
2023 SCImago Journal Rankings: 2.052
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChen, Tzu Yin-
dc.contributor.authorLoan, Phan Thi Kim-
dc.contributor.authorHsu, Chang Lung-
dc.contributor.authorLee, Yi Hsien-
dc.contributor.authorTse-Wei Wang, Jacob-
dc.contributor.authorWei, Kung Hwa-
dc.contributor.authorLin, Cheng Te-
dc.contributor.authorLi, Lain Jong-
dc.date.accessioned2021-04-08T03:08:48Z-
dc.date.available2021-04-08T03:08:48Z-
dc.date.issued2013-
dc.identifier.citationBiosensors and Bioelectronics, 2013, v. 41, n. 1, p. 103-109-
dc.identifier.issn0956-5663-
dc.identifier.urihttp://hdl.handle.net/10722/298579-
dc.description.abstractThe high transconductance and low noise of graphene-based field-effect transistors based on large-area monolayer graphene produced by chemical vapor deposition are used for label-free electrical detection of DNA hybridization. The gate materials, buffer concentration and surface condition of graphene have been optimized to achieve the DNA detection sensitivity as low as 1pM (10 M), which is more sensitive than the existing report based on few-layer graphene. The graphene films obtained using conventional PMMA-assisted transfer technique exhibits PMMA residues, which degrade the sensing performance of graphene. We have demonstrated that the sensing performance of the graphene samples prepared by gold-transfer is largely enhanced (by 125%). © 2012 Elsevier B.V. -12-
dc.languageeng-
dc.relation.ispartofBiosensors and Bioelectronics-
dc.subjectDNA sensing-
dc.subjectGold-transfer method-
dc.subjectLiquid-gated transistors-
dc.subjectLabel-free detection-
dc.subjectCVD graphene-
dc.titleLabel-free detection of DNA hybridization using transistors based on CVD grown graphene-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.bios.2012.07.059-
dc.identifier.pmid22944023-
dc.identifier.scopuseid_2-s2.0-84870821587-
dc.identifier.volume41-
dc.identifier.issue1-
dc.identifier.spage103-
dc.identifier.epage109-
dc.identifier.eissn1873-4235-
dc.identifier.isiWOS:000314191300012-
dc.identifier.issnl0956-5663-

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