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Article: Electrical detection of femtomolar DNA via gold-nanoparticle enhancement in carbon-nanotube-network field-effect transistors

TitleElectrical detection of femtomolar DNA via gold-nanoparticle enhancement in carbon-nanotube-network field-effect transistors
Authors
Issue Date2008
Citation
Advanced Materials, 2008, v. 20, n. 12, p. 2389-2393 How to Cite?
AbstractA significant sensitivity enhancement in electrical detection of DNA hybridization in SNFETs through the introduction of reporter DNA-AuNP conjugates in the hybridization step was investigated. The amplified change in drain current allowed to reliably determine the DNA concentration down to ca. 100 fM. Random networks of SWNTs with diameters between 1 and 3 nm and lengths between 5 and 10 μm were first grown onto SiO wafers using chemical vapor deposition techniques. SWNT network transistors (SNFETs) were fabricated in a top-contact device geometry, where 30 nm of a Ta electrodes were patterned on top of it by using standard lithography techniques. It was observed that SNFET-based biosensors and immunosensors may be adapted to detection of a variety of biomarkers for applications ranging from molecular diagnostics to in vitro diagnostics. 2
Persistent Identifierhttp://hdl.handle.net/10722/298462
ISSN
2020 Impact Factor: 30.849
2020 SCImago Journal Rankings: 10.707

 

DC FieldValueLanguage
dc.contributor.authorDong, Xiaochen-
dc.contributor.authorLau, Ching Man-
dc.contributor.authorLohani, Anup-
dc.contributor.authorMhaisalkar, Subodh G.-
dc.contributor.authorKasim, Johnson-
dc.contributor.authorShen, Zexiang-
dc.contributor.authorHo, Xinning-
dc.contributor.authorRogers, John A.-
dc.contributor.authorLi, Lain Jong-
dc.date.accessioned2021-04-08T03:08:28Z-
dc.date.available2021-04-08T03:08:28Z-
dc.date.issued2008-
dc.identifier.citationAdvanced Materials, 2008, v. 20, n. 12, p. 2389-2393-
dc.identifier.issn0935-9648-
dc.identifier.urihttp://hdl.handle.net/10722/298462-
dc.description.abstractA significant sensitivity enhancement in electrical detection of DNA hybridization in SNFETs through the introduction of reporter DNA-AuNP conjugates in the hybridization step was investigated. The amplified change in drain current allowed to reliably determine the DNA concentration down to ca. 100 fM. Random networks of SWNTs with diameters between 1 and 3 nm and lengths between 5 and 10 μm were first grown onto SiO wafers using chemical vapor deposition techniques. SWNT network transistors (SNFETs) were fabricated in a top-contact device geometry, where 30 nm of a Ta electrodes were patterned on top of it by using standard lithography techniques. It was observed that SNFET-based biosensors and immunosensors may be adapted to detection of a variety of biomarkers for applications ranging from molecular diagnostics to in vitro diagnostics. 2-
dc.languageeng-
dc.relation.ispartofAdvanced Materials-
dc.titleElectrical detection of femtomolar DNA via gold-nanoparticle enhancement in carbon-nanotube-network field-effect transistors-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/adma.200702798-
dc.identifier.scopuseid_2-s2.0-54249129491-
dc.identifier.volume20-
dc.identifier.issue12-
dc.identifier.spage2389-
dc.identifier.epage2393-
dc.identifier.issnl0935-9648-

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