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- Publisher Website: 10.1167/iovs.13-13674
- Scopus: eid_2-s2.0-84902440130
- PMID: 24833738
- WOS: WOS:000339485800043
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Article: Noninvasive measurement of scleral stiffness and tangent modulus in porcine eyes
Title | Noninvasive measurement of scleral stiffness and tangent modulus in porcine eyes |
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Authors | |
Keywords | Glaucoma Myopia Tangent modulus Noninvasive measurement Sclera |
Issue Date | 2014 |
Citation | Investigative Ophthalmology and Visual Science, 2014, v. 55, n. 6, p. 3721-3726 How to Cite? |
Abstract | Purpose. We investigated an indentation technique to measure the scleral stiffness and tangent modulus of porcine eyes. Methods. The scleral load-displacement responses were measured with a universal testing machine as a function of IOP in 15 porcine eyes ex vivo using a 5-mm diameter cylindrical flat-punch indenter. The scleral radius of curvature and scleral thickness were measured using a DSLR camera (Alpha 900) and a camera-mounted stereomicroscope (M205C), respectively. The relationships between scleral stiffness, tangent modulus, and IOP were examined. Results. The mean local scleral radius of curvature and scleral thickness were 7.86 ± 0.49 and 1.03 ± 0.14 mm, respectively. The average scleral stiffness and scleral tangent modulus of porcine eyes were 0.13 ± 0.02 N/mm and 0.20 ± 0.04 MPa at 15 mm Hg, respectively. The scleral stiffness and scleral tangent modulus were correlated positively with IOP (scleral stiffness, 0.989 < r < 0.999, P < 0.001; scleral tangent modulus, 0.989 < r < 0.999, P < 0.001). Conclusions. The scleral indentation technique can provide a noninvasive approach to measure scleral stiffness and tangent modulus. © 2014 The Association for Research in Vision and Ophthalmology, Inc. |
Persistent Identifier | http://hdl.handle.net/10722/298080 |
ISSN | 2023 Impact Factor: 5.0 2023 SCImago Journal Rankings: 1.422 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Leung, Leo K.K. | - |
dc.contributor.author | Ko, Match W.L. | - |
dc.contributor.author | Ye, Cong | - |
dc.contributor.author | Lam, David C.C. | - |
dc.contributor.author | Leung, Christopher K.S. | - |
dc.date.accessioned | 2021-04-08T03:07:38Z | - |
dc.date.available | 2021-04-08T03:07:38Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Investigative Ophthalmology and Visual Science, 2014, v. 55, n. 6, p. 3721-3726 | - |
dc.identifier.issn | 0146-0404 | - |
dc.identifier.uri | http://hdl.handle.net/10722/298080 | - |
dc.description.abstract | Purpose. We investigated an indentation technique to measure the scleral stiffness and tangent modulus of porcine eyes. Methods. The scleral load-displacement responses were measured with a universal testing machine as a function of IOP in 15 porcine eyes ex vivo using a 5-mm diameter cylindrical flat-punch indenter. The scleral radius of curvature and scleral thickness were measured using a DSLR camera (Alpha 900) and a camera-mounted stereomicroscope (M205C), respectively. The relationships between scleral stiffness, tangent modulus, and IOP were examined. Results. The mean local scleral radius of curvature and scleral thickness were 7.86 ± 0.49 and 1.03 ± 0.14 mm, respectively. The average scleral stiffness and scleral tangent modulus of porcine eyes were 0.13 ± 0.02 N/mm and 0.20 ± 0.04 MPa at 15 mm Hg, respectively. The scleral stiffness and scleral tangent modulus were correlated positively with IOP (scleral stiffness, 0.989 < r < 0.999, P < 0.001; scleral tangent modulus, 0.989 < r < 0.999, P < 0.001). Conclusions. The scleral indentation technique can provide a noninvasive approach to measure scleral stiffness and tangent modulus. © 2014 The Association for Research in Vision and Ophthalmology, Inc. | - |
dc.language | eng | - |
dc.relation.ispartof | Investigative Ophthalmology and Visual Science | - |
dc.subject | Glaucoma | - |
dc.subject | Myopia | - |
dc.subject | Tangent modulus | - |
dc.subject | Noninvasive measurement | - |
dc.subject | Sclera | - |
dc.title | Noninvasive measurement of scleral stiffness and tangent modulus in porcine eyes | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1167/iovs.13-13674 | - |
dc.identifier.pmid | 24833738 | - |
dc.identifier.scopus | eid_2-s2.0-84902440130 | - |
dc.identifier.volume | 55 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 3721 | - |
dc.identifier.epage | 3726 | - |
dc.identifier.eissn | 1552-5783 | - |
dc.identifier.isi | WOS:000339485800043 | - |
dc.identifier.issnl | 0146-0404 | - |