File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Comparative Study of Central Corneal Thickness Measurement with Slit-Lamp Optical Coherence Tomography and Visante Optical Coherence Tomography

TitleComparative Study of Central Corneal Thickness Measurement with Slit-Lamp Optical Coherence Tomography and Visante Optical Coherence Tomography
Authors
Issue Date2008
Citation
Ophthalmology, 2008, v. 115, n. 5, p. 796-801.e2 How to Cite?
AbstractPurpose: To evaluate the repeatability and reproducibility of central corneal thickness (CCT) measurements obtained by 2 anterior segment optical coherence tomography (OCT) imaging systems and to examine their agreements with ultrasound pachymetry. Design: Observational cross-sectional study. Participants: Fifty eyes from 50 healthy normal subjects were recruited. Methods: In one randomly selected eye in each subject, CCT was measured by slit-lamp OCT (SLOCT), Visante OCT, and ultrasound pachymetry. For anterior segment OCT measurements, both automatic and manual CCTs were obtained. Twenty-five of the 50 subjects were invited for 2 more visits within a week to evaluate repeatability and reproducibility of CCT measurement. Main Outcome Measures: Central corneal thickness measurement obtained by the 3 methods and their agreements. Intrasession and intersession within-subject standard deviation (S ), precision (1.96×S ), coefficient of variation (CV ) (100×S /overall mean), and intraclass correlation coefficient (ICC) were calculated to evaluate repeatability and reproducibility. Results: Good repeatability and reproducibility were found for both automatic and manual CCT measurements obtained by SLOCT and Visante OCT. For intrasession repeatability, CV and ICC values ranged between 0.9% and 1.2% and 0.96 and 0.98, respectively. For intersession reproducibility, the respective CV and ICC values ranged between 1.2% and 1.4% and 0.94 and 0.96. Although no significant difference was found between automatic/manual SLOCT measurements and ultrasound pachymetry, automatic Visante OCT CCT (535.7±30.2 μm) was significantly less than CCT with ultrasound pachymetry (550.3±31.14 μm) (P<0.001). In contrast, manual Visante OCT measurement (558.8±32.8 μm) was slightly higher than ultrasound pachymetry (P<0.001). Nevertheless, SLOCT and Visante OCT measurement of CCT had 95% limits of agreement comparable to that of ultrasound pachymetry. The best agreement was observed in the manual SLOCT measurement (95% limits of agreement between -15.5 and 11.7 μm). Conclusions: Both SLOCT and Visante OCT automatic and manual CCT measurements were reliable and showed comparable agreement with ultrasound pachymetry. Although the 2 anterior segment OCT imaging systems have similar design and working principles, clinicians should be aware of the differences in CCT measurement between the 2 anterior segment OCTs. © 2008 American Academy of Ophthalmology. w w w w w w
Persistent Identifierhttp://hdl.handle.net/10722/297964
ISSN
2023 Impact Factor: 13.1
2023 SCImago Journal Rankings: 4.642
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, Haitao-
dc.contributor.authorLeung, Christopher Kai Shun-
dc.contributor.authorWong, Lee-
dc.contributor.authorCheung, Carol Yim Lui-
dc.contributor.authorPang, Chi Pui-
dc.contributor.authorWeinreb, Robert Neal-
dc.contributor.authorLam, Dennis Shun Chiu-
dc.date.accessioned2021-04-08T03:07:21Z-
dc.date.available2021-04-08T03:07:21Z-
dc.date.issued2008-
dc.identifier.citationOphthalmology, 2008, v. 115, n. 5, p. 796-801.e2-
dc.identifier.issn0161-6420-
dc.identifier.urihttp://hdl.handle.net/10722/297964-
dc.description.abstractPurpose: To evaluate the repeatability and reproducibility of central corneal thickness (CCT) measurements obtained by 2 anterior segment optical coherence tomography (OCT) imaging systems and to examine their agreements with ultrasound pachymetry. Design: Observational cross-sectional study. Participants: Fifty eyes from 50 healthy normal subjects were recruited. Methods: In one randomly selected eye in each subject, CCT was measured by slit-lamp OCT (SLOCT), Visante OCT, and ultrasound pachymetry. For anterior segment OCT measurements, both automatic and manual CCTs were obtained. Twenty-five of the 50 subjects were invited for 2 more visits within a week to evaluate repeatability and reproducibility of CCT measurement. Main Outcome Measures: Central corneal thickness measurement obtained by the 3 methods and their agreements. Intrasession and intersession within-subject standard deviation (S ), precision (1.96×S ), coefficient of variation (CV ) (100×S /overall mean), and intraclass correlation coefficient (ICC) were calculated to evaluate repeatability and reproducibility. Results: Good repeatability and reproducibility were found for both automatic and manual CCT measurements obtained by SLOCT and Visante OCT. For intrasession repeatability, CV and ICC values ranged between 0.9% and 1.2% and 0.96 and 0.98, respectively. For intersession reproducibility, the respective CV and ICC values ranged between 1.2% and 1.4% and 0.94 and 0.96. Although no significant difference was found between automatic/manual SLOCT measurements and ultrasound pachymetry, automatic Visante OCT CCT (535.7±30.2 μm) was significantly less than CCT with ultrasound pachymetry (550.3±31.14 μm) (P<0.001). In contrast, manual Visante OCT measurement (558.8±32.8 μm) was slightly higher than ultrasound pachymetry (P<0.001). Nevertheless, SLOCT and Visante OCT measurement of CCT had 95% limits of agreement comparable to that of ultrasound pachymetry. The best agreement was observed in the manual SLOCT measurement (95% limits of agreement between -15.5 and 11.7 μm). Conclusions: Both SLOCT and Visante OCT automatic and manual CCT measurements were reliable and showed comparable agreement with ultrasound pachymetry. Although the 2 anterior segment OCT imaging systems have similar design and working principles, clinicians should be aware of the differences in CCT measurement between the 2 anterior segment OCTs. © 2008 American Academy of Ophthalmology. w w w w w w-
dc.languageeng-
dc.relation.ispartofOphthalmology-
dc.titleComparative Study of Central Corneal Thickness Measurement with Slit-Lamp Optical Coherence Tomography and Visante Optical Coherence Tomography-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ophtha.2007.07.006-
dc.identifier.pmid17916376-
dc.identifier.scopuseid_2-s2.0-42649140555-
dc.identifier.volume115-
dc.identifier.issue5-
dc.identifier.spage796-
dc.identifier.epage801.e2-
dc.identifier.isiWOS:000255614400007-
dc.identifier.issnl0161-6420-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats