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Article: Effectiveness of Pit and Fissure Sealants for Preventing and Arresting Occlusal Caries in Primary Molars: A Systematic Review and Meta-Analysis

TitleEffectiveness of Pit and Fissure Sealants for Preventing and Arresting Occlusal Caries in Primary Molars: A Systematic Review and Meta-Analysis
Authors
KeywordsPit and fissure sealants
Occlusal caries
Prevention
Arrest
Primary molars
Issue Date2020
PublisherMosby, Inc. The Journal's web site is located at http://www.jebdp.com
Citation
Journal of Evidence Based Dental Practice, 2020, v. 20 n. 2, p. article no. 101404 How to Cite?
AbstractObjective: The use of pit and fissure sealants have been well supported in permanent teeth, but no concrete evidence is available to support this procedure in primary molars. This review aims to systematically assess randomized controlled trials and summarize the evidence on the effectiveness of different sealants in prevention and arrest of the pit and fissure occlusal caries in primary molars of children. Materials and methods: Four electronic databases were searched from inception to March 2018. Seven studies were included in the qualitative and quantitative syntheses. Two reviewers independently selected studies, extracted data, assessed risk of bias using the revised Cochrane risk of bias tool, and evaluated the certainty in the evidence adopting the Grading of Recommendations Assessment Development and Evaluation approach. Odds ratio and retention rate of different sealants were recalculated and analyzed. Results: This review identified no significant difference in the overall caries incidence and progression when evaluated over 24 months between (1) resin-based sealant (RBS) and glass ionomer sealants (GIS) or resin-modified GIS; (2) conventional and newly developed RBS; (3) autopolymerized and light-polymerized RBS; (4) RBS with topical fluoride application and topical fluoride alone; and (5) RBS with topical fluoride application and resin infiltration with topical fluoride application. The pooled estimates of the mean retention rates of RBS and GIS on primary molars over an 18-months period were 85.94% and 23.18%, respectively. The certainty in the evidence of each outcome was determined as low or very low mainly because of high risk of overall bias and imprecision. Conclusion: There are currently insufficient well-controlled randomized controlled clinical trials to determine whether sealants are beneficial in preventing or arresting noncavitated occlusal caries in the primary molars.
Persistent Identifierhttp://hdl.handle.net/10722/297156
ISSN
2023 Impact Factor: 4.1
2023 SCImago Journal Rankings: 1.023
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, PPY-
dc.contributor.authorSARDANA, D-
dc.contributor.authorEkambaram, M-
dc.contributor.authorLee, GHM-
dc.contributor.authorYiu, CKY-
dc.date.accessioned2021-03-08T07:14:57Z-
dc.date.available2021-03-08T07:14:57Z-
dc.date.issued2020-
dc.identifier.citationJournal of Evidence Based Dental Practice, 2020, v. 20 n. 2, p. article no. 101404-
dc.identifier.issn1532-3382-
dc.identifier.urihttp://hdl.handle.net/10722/297156-
dc.description.abstractObjective: The use of pit and fissure sealants have been well supported in permanent teeth, but no concrete evidence is available to support this procedure in primary molars. This review aims to systematically assess randomized controlled trials and summarize the evidence on the effectiveness of different sealants in prevention and arrest of the pit and fissure occlusal caries in primary molars of children. Materials and methods: Four electronic databases were searched from inception to March 2018. Seven studies were included in the qualitative and quantitative syntheses. Two reviewers independently selected studies, extracted data, assessed risk of bias using the revised Cochrane risk of bias tool, and evaluated the certainty in the evidence adopting the Grading of Recommendations Assessment Development and Evaluation approach. Odds ratio and retention rate of different sealants were recalculated and analyzed. Results: This review identified no significant difference in the overall caries incidence and progression when evaluated over 24 months between (1) resin-based sealant (RBS) and glass ionomer sealants (GIS) or resin-modified GIS; (2) conventional and newly developed RBS; (3) autopolymerized and light-polymerized RBS; (4) RBS with topical fluoride application and topical fluoride alone; and (5) RBS with topical fluoride application and resin infiltration with topical fluoride application. The pooled estimates of the mean retention rates of RBS and GIS on primary molars over an 18-months period were 85.94% and 23.18%, respectively. The certainty in the evidence of each outcome was determined as low or very low mainly because of high risk of overall bias and imprecision. Conclusion: There are currently insufficient well-controlled randomized controlled clinical trials to determine whether sealants are beneficial in preventing or arresting noncavitated occlusal caries in the primary molars.-
dc.languageeng-
dc.publisherMosby, Inc. The Journal's web site is located at http://www.jebdp.com-
dc.relation.ispartofJournal of Evidence Based Dental Practice-
dc.subjectPit and fissure sealants-
dc.subjectOcclusal caries-
dc.subjectPrevention-
dc.subjectArrest-
dc.subjectPrimary molars-
dc.titleEffectiveness of Pit and Fissure Sealants for Preventing and Arresting Occlusal Caries in Primary Molars: A Systematic Review and Meta-Analysis-
dc.typeArticle-
dc.identifier.emailLee, GHM: lee.gillian@hku.hk-
dc.identifier.emailYiu, CKY: ckyyiu@hkucc.hku.hk-
dc.identifier.authorityLee, GHM=rp01594-
dc.identifier.authorityYiu, CKY=rp00018-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jebdp.2020.101404-
dc.identifier.pmid32473795-
dc.identifier.scopuseid_2-s2.0-85083255092-
dc.identifier.hkuros321604-
dc.identifier.volume20-
dc.identifier.issue2-
dc.identifier.spagearticle no. 101404-
dc.identifier.epagearticle no. 101404-
dc.identifier.isiWOS:000537499400003-
dc.publisher.placeUnited States-

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