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- Publisher Website: 10.3389/fbioe.2020.601246
- Scopus: eid_2-s2.0-85098223099
- PMID: 33363130
- WOS: WOS:000601272300001
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Article: Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective
Title | Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective |
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Authors | |
Keywords | polysaccharide-based nanomaterials polysaccharides ocular drug delivery nanocarriers nano |
Issue Date | 2020 |
Publisher | Frontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/bioengineering_and_biotechnology |
Citation | Frontiers in Bioengineering and Biotechnology, 2020, v. 8, p. article no. 601246 How to Cite? |
Abstract | Ocular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues. |
Persistent Identifier | http://hdl.handle.net/10722/295498 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 0.893 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Yu, H | - |
dc.contributor.author | Wu, W | - |
dc.contributor.author | Lin, X | - |
dc.contributor.author | Feng, Y | - |
dc.date.accessioned | 2021-01-25T11:15:45Z | - |
dc.date.available | 2021-01-25T11:15:45Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Frontiers in Bioengineering and Biotechnology, 2020, v. 8, p. article no. 601246 | - |
dc.identifier.issn | 2296-4185 | - |
dc.identifier.uri | http://hdl.handle.net/10722/295498 | - |
dc.description.abstract | Ocular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues. | - |
dc.language | eng | - |
dc.publisher | Frontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/bioengineering_and_biotechnology | - |
dc.relation.ispartof | Frontiers in Bioengineering and Biotechnology | - |
dc.rights | This Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | polysaccharide-based nanomaterials | - |
dc.subject | polysaccharides | - |
dc.subject | ocular drug delivery | - |
dc.subject | nanocarriers | - |
dc.subject | nano | - |
dc.title | Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective | - |
dc.type | Article | - |
dc.identifier.email | Lin, X: linxiang@hku.hk | - |
dc.identifier.authority | Lin, X=rp02623 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3389/fbioe.2020.601246 | - |
dc.identifier.pmid | 33363130 | - |
dc.identifier.pmcid | PMC7758246 | - |
dc.identifier.scopus | eid_2-s2.0-85098223099 | - |
dc.identifier.hkuros | 321012 | - |
dc.identifier.volume | 8 | - |
dc.identifier.spage | article no. 601246 | - |
dc.identifier.epage | article no. 601246 | - |
dc.identifier.isi | WOS:000601272300001 | - |
dc.publisher.place | Switzerland | - |