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Article: Chemical Protein Synthesis: Advances, Challenges, and Outlooks

TitleChemical Protein Synthesis: Advances, Challenges, and Outlooks
Authors
pTan, YWU, HWEI, TLi, X
Issue Date2020
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html
Citation
Journal of the American Chemical Society, 2020, v. 142 n. 48, p. 20288-20298 How to Cite?
DOI: http://dx.doi.org/10.1021/jacs.0c09664
AbstractContemporary chemical protein synthesis has been dramatically advanced over the past few decades, which has enabled chemists to reach the landscape of synthetic biomacromolecules. Chemical synthesis can produce synthetic proteins with precisely controlled structures which are difficult or impossible to obtain via gene expression systems. Herein, we summarize the key enabling ligation technologies, major strategic developments, and some selected representative applications of synthetic proteins and provide an outlook for future development.
Persistent Identifierhttp://hdl.handle.net/10722/294586
ISSN
0002-7863
2023 Impact Factor: 14.4
2023 SCImago Journal Rankings: 5.489
ISI Accession Number ID
WOS:000596904700002

 

DC FieldValueLanguage
dc.contributor.authorpTan, Y-
dc.contributor.authorWU, H-
dc.contributor.authorWEI, T-
dc.contributor.authorLi, X-
dc.date.accessioned2020-12-08T07:39:03Z-
dc.date.available2020-12-08T07:39:03Z-
dc.date.issued2020-
dc.identifier.citationJournal of the American Chemical Society, 2020, v. 142 n. 48, p. 20288-20298-
dc.identifier.issn0002-7863-
dc.identifier.urihttp://hdl.handle.net/10722/294586-
dc.description.abstractContemporary chemical protein synthesis has been dramatically advanced over the past few decades, which has enabled chemists to reach the landscape of synthetic biomacromolecules. Chemical synthesis can produce synthetic proteins with precisely controlled structures which are difficult or impossible to obtain via gene expression systems. Herein, we summarize the key enabling ligation technologies, major strategic developments, and some selected representative applications of synthetic proteins and provide an outlook for future development.-
dc.languageeng-
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html-
dc.relation.ispartofJournal of the American Chemical Society-
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in [JournalTitle], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://pubs.acs.org/page/policy/articlesonrequest/index.html].-
dc.titleChemical Protein Synthesis: Advances, Challenges, and Outlooks-
dc.typeArticle-
dc.identifier.emailpTan, Y: tanyi@hku.hk-
dc.identifier.emailLi, X: xuechenl@hku.hk-
dc.identifier.authorityLi, X=rp00742-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/jacs.0c09664-
dc.identifier.pmid33211477-
dc.identifier.scopuseid_2-s2.0-85097892406-
dc.identifier.hkuros320346-
dc.identifier.volume142-
dc.identifier.issue48-
dc.identifier.spage20288-
dc.identifier.epage20298-
dc.identifier.isiWOS:000596904700002-
dc.publisher.placeUnited States-

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