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- Publisher Website: 10.1016/j.bbmt.2015.02.023
- Scopus: eid_2-s2.0-84947487201
- PMID: 25748273
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Article: Routine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value
Title | Routine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value |
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Authors | |
Keywords | Allogeneic Abdominal Computed tomography Stem cell transplantation |
Issue Date | 2015 |
Citation | Biology of Blood and Marrow Transplantation, 2015, v. 21, n. 6, p. 1132-1135 How to Cite? |
Abstract | © 2015 American Society for Blood and Marrow Transplantation. The diagnostic utility of obtaining chest and abdomen computed tomography (CT) to evaluate for invasive fungal infection (IFI) before and after hematopoietic stem cell transplant (HSCT) remains unclear. The study was conducted as a quality improvement project. Chest and abdomen CT of patients who underwent an allogeneic HSCT over a 13-month period were reviewed. Scans included those performed pretransplant in all patients and days 0 to 100 post-transplant in selected patients. Sixty-six patients had chest and abdomen CT scans pretransplant. Chest CT was suggestive of IFI in 9 patients (13.6%), including 3 patients with prior history of IFI. After transplant, 37 patients had an initial chest CT and 14 patients an initial abdominal CT. The first chest CT post-transplant was suggestive of IFI in 3 patients; all had an abnormal CT pretransplant. After the initial post-transplant evaluation, 15 patients had 28 additional CT scans of the chest and 12 patients 19 additional CT scans of the abdomen. An abnormal chest CT with proven evidence of IFI was seen in only 1 patient. None of the 99 abdominal CT scans performed pre- or post-transplant had evidence of IFI. There is little benefit in obtaining abdominal CT scans in HSCT patients for detecting IFI either pre- or post-transplant. |
Persistent Identifier | http://hdl.handle.net/10722/294509 |
ISSN | 2022 Impact Factor: 4.3 2020 SCImago Journal Rankings: 2.301 |
PubMed Central ID |
DC Field | Value | Language |
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dc.contributor.author | Kaste, Sue C. | - |
dc.contributor.author | Kaufman, Robert A. | - |
dc.contributor.author | Sunkara, Anusha | - |
dc.contributor.author | Kang, Guolian | - |
dc.contributor.author | Morris, Cynthia | - |
dc.contributor.author | Leung, Wing | - |
dc.contributor.author | Srinivasan, Ashok | - |
dc.date.accessioned | 2020-12-03T08:22:54Z | - |
dc.date.available | 2020-12-03T08:22:54Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Biology of Blood and Marrow Transplantation, 2015, v. 21, n. 6, p. 1132-1135 | - |
dc.identifier.issn | 1083-8791 | - |
dc.identifier.uri | http://hdl.handle.net/10722/294509 | - |
dc.description.abstract | © 2015 American Society for Blood and Marrow Transplantation. The diagnostic utility of obtaining chest and abdomen computed tomography (CT) to evaluate for invasive fungal infection (IFI) before and after hematopoietic stem cell transplant (HSCT) remains unclear. The study was conducted as a quality improvement project. Chest and abdomen CT of patients who underwent an allogeneic HSCT over a 13-month period were reviewed. Scans included those performed pretransplant in all patients and days 0 to 100 post-transplant in selected patients. Sixty-six patients had chest and abdomen CT scans pretransplant. Chest CT was suggestive of IFI in 9 patients (13.6%), including 3 patients with prior history of IFI. After transplant, 37 patients had an initial chest CT and 14 patients an initial abdominal CT. The first chest CT post-transplant was suggestive of IFI in 3 patients; all had an abnormal CT pretransplant. After the initial post-transplant evaluation, 15 patients had 28 additional CT scans of the chest and 12 patients 19 additional CT scans of the abdomen. An abnormal chest CT with proven evidence of IFI was seen in only 1 patient. None of the 99 abdominal CT scans performed pre- or post-transplant had evidence of IFI. There is little benefit in obtaining abdominal CT scans in HSCT patients for detecting IFI either pre- or post-transplant. | - |
dc.language | eng | - |
dc.relation.ispartof | Biology of Blood and Marrow Transplantation | - |
dc.subject | Allogeneic | - |
dc.subject | Abdominal | - |
dc.subject | Computed tomography | - |
dc.subject | Stem cell transplantation | - |
dc.title | Routine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1016/j.bbmt.2015.02.023 | - |
dc.identifier.pmid | 25748273 | - |
dc.identifier.pmcid | PMC4624397 | - |
dc.identifier.scopus | eid_2-s2.0-84947487201 | - |
dc.identifier.volume | 21 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 1132 | - |
dc.identifier.epage | 1135 | - |
dc.identifier.eissn | 1523-6536 | - |
dc.identifier.issnl | 1083-8791 | - |